Cocaine in the Brain

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Biology 202
2000 First Web Report
On Serendip

Cocaine in the Brain

Melissa Hoegler

"Cocaine delivers an intensity of pleasure - and despair - beyond the bounds of normal human experience."

During the 1980s, Partnership for a Drug Free America began airing commercials that seem to either frighten or educate people about the use of illegal drugs. One of these commercials avowed, "No one ever says, 'I want to be a junkie when I grow up'." The comment is obvious, but very true. Probably very few people aspire to be drug addicts. But it happens, everyday. Why? What is so good about a drug that can potentially destroy a person's body? How does it work? What are its effects on the brain? Why is it so hard to quit?

Cocaine (C17H21NO4) comes from the leaf of an Erythroxylon coca bush. It is a drug that effects the central nervous system. It causes feelings of euphoria, pleasure, increased energy and alertness. People under the influence of cocaine often do not feel the need for food or sleep. They also feel energetic and may talk a lot. However, depending on factors such as environment, dosage, and the manner in which the drug is taken, cocaine can have adverse effects such as violent, erratic behavior, dizziness, paranoia, insomnia, convulsions, and heart failure to name a few. Long- term effects of cocaine include, but are not limited to strokes, heart attacks, seizures, loss of memory, and decrease in learning capability (1).

People may not always know the exact consequences of the drug they are taking, however, chances are that they do know that the drug is unhealthy for them. Schools across the country educate about the dangers of drug use and abuse through programs like D.A.R.E., television stations show anti-drug advertisements as a public service, and even city buses blazon anti-drug propaganda. People are aware that very rarely does anything good come from drug use, and still, everyday people fall victim to drugs. Why do people succumb to the urge to try drugs? It feels good...why else?

When a person takes cocaine, it causes a rush. There is between one or two minutes of intense pleasure. This is followed by five to 8 minutes of euphoria, then as the high comes down, an overwhelming urge for more, which may last for a day. (3) When a user is between cocaine doses or halts usage, the opposite effects occur. The user is depressed and tired (2).

Cocaine is attractive to users because it triggers dopamine. Dopamine is a neurotransmitter that is present in many regions of the brain. In normal mice, the introduction of cocaine increases dopamine by 150 percent. Dopamine regulates movement, emotion, motivation, and the feeling of pleasure. In a normal brain, dopamine is released by a neuron into a synapse and then it moves to dopamine receptors on other neurons. It is then moved back to the neuron that transmitted the dopamine initially.

When cocaine enters the area of the brain where the dopamine is located, it blocks the reuptake pumps that remove the dopamine from the synapse of the nerve cell. Thus, more dopamine gathers at the synapse and feelings of intense pleasure result. This feeling continues until cocaine is naturally removed from the system (2). Research findings by the National Institute of Drug Addiction (NIDA) demonstrate that cocaine not only effects the level of dopamine in the brain, but also the level of seratonin. In a study using mice without dopamine transporters, the mice were given cocaine and they still experienced rewarding effects. This was obvious because the animals kept on attempting to get or self-administer more. These researchers speculate that more than one neurotransmitter is responsible for the pleasurable feeling cocaine yields (2). Although main hypothesis as to why cocaine is so pleasurable, is that it alters levels of dopamine, norepinephrine, and seratonin, some scientists report that cocaine effects approximately 90 different parts of the brain, not just the two main regions of the amygdala and the nucleus accumbens. However, it is interesting that it is these two regions of the brain that remain active after the cocaine has left the system, and the powerful, uncontrollable desire for the drug has set in. (3)

The first time people use cocaine and its effects fade, they want more. Such is the nature of the drug. The main reason cocaine use continues is the need to experience the "high" and the development of dependence. Dependence is, "the need to maintain a level of the drug in the brain to both satisfy the need and stimulate the reward center, and avoid physical withdrawal symptoms" (5). There is continual research occurring about dependence and how it can be streamlined.

It was recently discovered through newer imaging techniques that cocaine hinders blood flow. This is why is it can cause brain damage or defects. Recent research demonstrates that if a cocaine user even thinks about cocaine, the blood flow is altered . This suggests that the addictive nature of the drug is stronger than we think, because simply thinking about it produces similar results in addicts' brains' (4). This is likely to be a result of the way in which cocaine changes the structure of an abuser's brain. For example n experiments done with lab rats, scientists reported that after repeated exposure to cocaine, the rats' dendrites changed by becoming bigger and denser. This means that an increase in synaptic connectivity results from cocaine use which triggers people and animals to work harder to attain the drug (6).

Scientists are working furiously for a way to combat cocaine addiction. They specifically are examining the genetic factors that contribute to the addiction (5). However, even if scientists do identify all of the factors that cause addiction, they are still faced with the dilemma of how exactly to stop the addiction. New hope to end cocaine addiction lies in experimental drugs, such as one that is used to treat epilepsy and holistic approaches such as acupuncture.

Although it may seem like science knows a great deal about addiction and the effects of cocaine, scientific knowledge still cannot make the cocaine problem disappear. There is no sure cure for cocaine addiction. Once you try the drug, addiction strikes randomly, like a bullet in a game of Russian roulette. There is no cure for the addiction. Before trying the drug, really think, is a moment of pleasure worth a lifetime of pain?

 

WWW Sources

1)Facts About Cocaine, The Addiction Research Foundation out of Canada produced this site. It contains basic information about cocaine, its effects, and facts about addiction.

2)Cocaine's Pleasurable Effects May Involve Multiple Chemical Sites, This site is a part of NIDA notes. It explains theories about the way cocaine effects the brain. There is a picture of how cocaine effects the neurotransmitter .

3) Intricate Effects of Cocaine on the Brain Seen In Scans , Some older (3 years), but more controversial research about cocaine use. It shows cool pictures of brain scans.

4) Researches see how cocaine Affects the Brain, Highlights an experiment involving images of butterflies and cocaine. Interesting results.

5) New Targets in the Brain's Reward CenterThis article concentrates on the genetic causes of coke addiction.

6) Repeated Exposure To Cocaine Alters Brain Structure", Talks about the long term effect of coke on the brain and nerves.



Comments made prior to 2007
You made a good speach but if you have not tried it yourself you should not speak about it. There is no addiction it is all about getting as high, butalso if you smoke or are just a weak person with no will-power than yes it will make you steal or get in so deep you have to take yourself out of it or this cruel world. I just thought incase you have not tried it you may never want to, because once you do even just one little line you feel alot different the next day, and not to mention if you do it enough you will eventually move a step up to cooking or smoking it which is ten times worse. Depending what you think is worth losing, your brain and nasial cavity, or your lungs,stomach, and chest pieces you choke or cough up in chunks with a bunch of black shit.Any ways I was just going through alot of these cocain sites and stuff so I'm sorry to have to go through with this but everyone got pretty much the same thing because ...what I am reading... may be true but these people like I said they sound like they have not it or they are taking their stuff straight from books or sites. Cause if not they would see that it is the weak minded people whocannot control the addiction whichis not an addiction it just seems like it because it is expensive and there is never enough at the end and if you cannot control or handle the fiend phase you are screwed and will buy more if obtainable.Sorry for writing so much but like Isaid earlier lot of these are out of a book and if it says comment on I did. Personally Your speech thing is pretty good it just needs some" insight from an user it would make your speech more powerful". sorry for no email I would like to keep in touchover email but I don't know how to make one. Last thing board people and loners usually have the worst will-power after the smokers or the daily pot smokers usually are the weakest or most likely to start or becone addicted "remember this their is no addiction only the love for something, also it takes 25 dayes to gain or break a habit depending on how powerfull the person asmoker like me it may only take a week or so because I am already addicted to something and alot of the tim change is good" sorry for wasting your time if you actually decided to actually read this but like I said I am baked off it and reading what it is doing to my body and because it is a fridayor saturday thing since i do work monday to friday. any ways if possible write back you can cut me up in your smart way like everyone else does for doing it but if I felt I had a reason although you always crave it it is all about fulfilling that feeling without going overboard with it, that inmy opinion although it hurts the body same way in my opinion that is the difference between me "an user" and an every day addict which by the way does not mean they are addicted they may just like it for the fun or great high it gives you every time.....THANK YOU FOR READING ... Shane Skylar, 9 November 2006

 

 

where the cool pictures mentioned. just another article with pictures. dont need to see what cocaine looks like but what the brain looks like after extended use ... Kelley, 22 November 2006

Comments

jerzeety's picture

my girls an ex addict

My girl used to get high and I can tell that there's damage .she's slow to discover error and live and responds like she's still a teenager before she got high... she clueless to lots of things. And every weekend she wants to g out or eateat

Serendip Visitor's picture

TUNING THE CORNER

THE ONLY WAY TO CURE SOMETHING INCURABLE IS TOO GO TO THE SOURCE. THE ONLY ONE WHO HAS ALL THE ANSWERS AND ALL THE SOLUTIONS TO ADDICTIONS IS THE ONE WHO CREATED EVERYTHING. SO BROTHERS AND SISTERS PLEASE OPEN YOUR HEARTS FIND A SIMPLE AA PROGRAMME. AND YOU BE THE ONE WHO REALLY WANTS TO QUIT YOU BE THE ONE WHO GOES TO THE MOST HIGH THE GOD OF THE BIBLE THE CREATOR OF JESUS MOSES ETC... AND YOU ASK HIM TO WORK ON A CELLULAR LEVEL TO HEAL US FROM THIS DREADFUL ADDICTION. 15 DAYS CLEAN. THE COME UP. AMEN AMEN AMEN

tony borg's picture

cocaine

please dont bring religion into drug addiction cos ur gonna piss people off.vive been a coke addict for over 20 yrs and ive tried everything coke annon meetings, rehab, both were a waste of time cos there are toovmany jesus freaks like yourself. i was forced to leave rehab cos i refused to do bible studdies. i wasvthere for my addiction, not to read about shit that can never be proven. the only proper help ive had was macs project in wimbledon s. london. its a charity run centre where all staff are ex addicts and know exactly what we are feeling. they gave me the care and support and tools i needed to help myself. i moved away and was clean for 18 months but sadly found coke in my life again. im having hard time at the min with using but where i moved to 160 miles away they do not have the help anaddict needs here, just the usual councelors that read out of text books that dont have anyvidea what we are really going thru. i cant go back to london as i moved to lincoln lincs for custody of my son witch ive hadvfor 3 yrs now. i just gotta try my hardest with the tools ivevbeen given to quit. DO NOT EVER PREAcH GOD ON A SITE LIKE THIS

Rich's picture

re addiction and relapse

Hey I just found myself here and was moved by your response to the person pushing religion. I was never into cocaine but even after 10 years sober I struggle with my feelings. I left AA after 9 years cos I hated them all and their religion. After a year of trying to do life alone I went back (slowly at first) to different meetings and now I'm trying to share more but its not easy because I still don't trust people or the whole god thing. . .however. . . I have had a few moments of what you might call peace as a result of being in meetings. But its usually because I tried to share, and definitely because I like one or two of the people that go. I shared the other day that I don't believe in god and that i don't say that word during the serenity prayer because I'm a rebel. . .and they laughed 'with me' not at me which felt good. And it felt good when one of the people I like came up after and was complementary about my honest sharing. You and me and everyone, we want to feel good. I realise how many conditions I set on what I will and wont let in though, and I guess I just make it hard on myself a lot of the time. Hope your doing ok. Did you ever get to the Buddhist temple in Wimbldon. . . its amazing!

thomas b's picture

Total Abstinance

And by the way-when i say total abstinence - i mean not by doing this on your own - again, i quote - “Problems cannot be solved with the same mind set that created them.” ― Albert Einstein -

That being said-if you have tried total abstinence on your own - i will visit you at either your funeral or a mental ward - my suggestion is a 12 stwelve step program.

And remember that it isnt a feel good program. We spent too much time on making ourselves feel good at the expense of others. This is a living well program. And making others feel good about us program. And a program of salvation from the selfish decision we made in getting ourselves involved in the first place.

thomas b's picture

What Awaits

to those of you whom think using cocaine is a controllable habit, i can inform you that what you are engaging in is the development of a pathological illness that starts the minute you began using. it is why the call this a cunning, baffling, and powerful disease. This is truly a pathological illness furbished by construction of ones own ego in a manner that really just implodes upon itself.
A quote if you will - “Problems cannot be solved with the same mind set that created them.” ― Albert Einstein. Essentially the ego mind serves of a purpouse of protecting itself and its choices. Its rationalizations are used in the defense of its own choices, or mistakes (such as beginning the cycle of cocaine addiction). As a user continues down this path, and the using becomes greater, their own mind, the same mind and thought process that made the "rational" decision of trying cocaine, goes through various stages of as follows:

denial
arguing against an anxiety provoking stimuli by stating it doesn't exist
denying that your physician's diagnosis of cancer is correct and seeking a second opinion

projection
placing unacceptable impulses in yourself onto someone else
when losing an argument, you state "You're just Stupid;" homophobia

rationalization
supplying a logical or rational reason as opposed to the real reason
stating that you were fired because you didn't kiss up the the boss, when the real reason was your poor performance

reaction formation
taking the opposite belief because the true belief causes anxiety
having a bias against a particular race or culture and then embracing that race or culture to the extreme

suppression
pushing into the unconscious
trying to forget something that causes you anxiety

etc....etc....

as addiction continues, the pathology of your thinking accutally becomes designed to sabatoge you to continue using. It's really why the scientific and health comunity have classified addiction as a disease and mental illness.

I myself started the same way as Mr.:

haha
Submitted by love drug (guest) on Sun, 04/03/2011 - 10:15pm.
seriously the drug isn't anything like some of these comments have said.. maybe if you have grown up around nothing exciting, you will find that cocaine is the best thing thats ever happened to you

Woh woh woh. Take there own
Submitted by Tim (guest) on Mon, 10/17/2011 - 10:26pm.
Woh woh woh. Take there own life from a line. Ignorance is bliss.... Remember that. Are you one of the people telling our kids weed will kill you. Coke isnt really a problem in moderation

Essentially what these messengers comments are simply constitue the rational of their own diseased minds reassurement of denial, rationalization, etc. What im trying to say is that the minute drug abuse starts, you become your greatest enemy, The symptoms of depression which amost everyone on this page talks about is the same pathalogical mind defeating itself in an effort to either continue using or essentially commit suicide. Its the same mind at a different stage of the game. The same mind that created addiction, denied yourself about it, rationalized it, swore off from using, etc. The only difference is as this cyclke continues, your biochemistry changes. Once depleted of seratonin, neuropenephrine, etc, your mind creates self defeating thoughts of depression. As you no longer are on your favorite medicine. Thus when you use, the depression is gone, and the thoughts become re-assuring of why it is ok to use. Once the coke is gone, the depressive nature of your own mind comes back. Trust me, I know. I come from a polydrug use background including major cocaine binges, ecstasy, daily pot use, and heavy alchohol. I have done the whole, quit coke but conitnue drinking. Quit drinking and coke but conitnue smoking. Quit everywthing cold turkey then go back. Just drink and refrain from everything else. Iv had disabling depression, visits with the mental ward, anti depressant medications, etc. I went all the way to the point of literally a consciece hell. I could only think about commiting suicide all day.

What saved my ass so far? I have 21 months clean and sober. Completely clean and sober. I checked into rehab. I dived into a 12 step program and never left. Now how is my life? I have a car again, i have my career being re-established in mortgage banking. I work my program to the teeth and wire, am activer in sponsership. and regularly attend meetings. My depression is completely gone. I dont think about using cocaine at all. My thoughts about drinking alchohol are nill. And the pot, well please. We have bigger fish here to fry. So what can I say - for those of you whom are older-i havent seen one single case, at all, reflecting any positive outcome from cocaine use. For those of you whom are young, i know whom you are. Iv been there. The whole this is easy, I can control this, the craving is gone in a few days, so why is everyone so freaked out about it mindset. Why we cant stop despite all evidence suggesting we should? Again, this is a pathological illness. I dont know why. Ones own ego mind simply wont give the user that opportunity until a sufficient bottom is reached. Then, for a brief moment, whats called a "moment of clarity" is acquired, some which users act on and get help, some which users wig out on and simply refrain for months, years, until the depression gets so bad they go back to using or commit suicide, or which most users do, which is fucking just ignore and kill with a couple drinks after yet another coke bender.

The one thing i think almost everyone here can agree on is as follows:

1) Alcohol is usually the first drug cocaine addicts use, often addictively. (2) Alcohol is the drug abstinent cocaine addicts most often use before relapsing to cocaine. That is, alcohol is the most common reason for relapse to cocaine. (3) Because most cocaine addicts are alcoholics, effective treatment exists for them.

Thus the only solution for this whole mess we all got ourselves into total abstinence. Or suicide. I chose the former myself.

M. Craig Jewett's picture

Opinions, Pearls of Wisdom, Resentment & Just Plain Stupid

where do I start...well, reading these posts really caught me off gaurd a little bit. I went from laughing, to rage, to W.T.F.? to rage, to , well you get the idea. There was only one post that actually sent me past marginally annoyed. The genius going on and on about how Narconon "ripped him off, it didn't work". How this incredible injustice had been thrust upon him. He even states he stayed clean and sober while he was inpatient, not until he left di Narconons horrible practices fail him by not reaching out its far reaching, all knowing hand to bitch slap the tooter, or crack pipe, or syringe out of his "im at a fuckin coke party just for the chicks cuz i dont get high" attitude. I could go on forever ripping him to shreds on each and every twisted, misleading word he wrote that are dripping with no fucking accountability, ummm denial, immaturity, oh ya, the one crowning jewel. Just plain ol' textbook ADDICT MENTALITY" The natrue of being "in your disease" is you are moderately delusional, and the very fundamental operating sytem of delusional is...you cant see it because you are delusional. what a fucking paradox huh! My biggest problem with that post is it could be...IS very dangerous. Potentially keeping someone out of treatment. PLUS....Narconon? really? I cant even get started on that one...but lets just say , if recovering from addiction was as easy , and 90% effective as they lead you or want you to believe, then EVERYONE WOULD DO IT!. Also, I know, or at least hear that 12-Step programs aren't for everyone. Yes they are, it is something that definately has to be approached with an open mind, which, we as addicts are not real famous for. Ok...i need to make a point now.
Drug/Alcohol rehab works. 12 Steps A.A., works. The only other options are you quit on you own, through will power, reverse osthmosis, or obsessing on your work, wife, hobby. Then there is Jails and Prisons. LOL, over the entire history of mankind, encarciration DOES NOT WORK. Why do you think that now even Prisons are becoming privatized. owned by a private, non-government entity...because they make money....LOTS of it. They are the new healthcare cashcow.
If you have a problem, and you know it. If you keep using/drinking in the face of certain and severe consequences. If you experience the phenomenon of CRAVINGS. Normal, nonaddicts dont experience that! not with short term use...if you continue to pick a day to quit, but find yourself over and over again, AGAINST YOUR WILL, back at the liquor store or connections. You are ADDICT. wether its beer, whiskey, heroin, or bath salt...(i know , right?) you will do horrible things to just change the way you feel. I just fing love it when people say we are weak....lol NO SHIT! YA THINK? WHAT WAS YER 1ST FUCKING CLUE? Damn right I am weak when it comes to "the power of choice" once i have put a substance in my body. I completely lose all ability to make simple decisions where the well being of myself and loved ones are concerned. But, if I get involved in a purpose, if I quit thinking all day evry day about how I feel, and instead, start to actually consider how others feel. And a step futher is, how MY ACTIONS, THOUGHTS, WORDS, INTENTIONS, MOTIVES negatively affect those around me....if I do this, soon, I start to get a little confidence, self esteem, INTEGRITY. Thats the big one....that means will I do the right thing, even when no one else will know.....heavy huh? And can I do some nice things for people, or prinicpals, or institutions without bring attention to myself. You know....doing a victory lap to basque in the warm after-glow of your most charitable and selfless act....lol
Look, 99.9% of us, addicts/alcoholics are complete monsters, complete animals when loaded, but take that away and we are tolerable for a while, but replace it with an actual desire to help. If you are not part of the solution, you are the fing proble, Quit whining about the treatment center that you f'd off you fams money cuz you are a spoiled lil bitch with entitlement isssues, quit pointing fingers at the bad bad dad that that called you stupin when you were a kid. Change the way you act and it WILL change the way you feel.

Hollimommy's picture

Not addictive?

As the wife of an addict, I can personally attest to the addictive qualities of the drug and the psychotic delusions it fosters. I know I spent 5 years being tortured and pushed around by someone who had SEVERE persecution complex. He believed I was hiding all kinds of drugs all over the house, doing them in secret. He used to scrape gummy dirt from under the sink and call it black tar heroin, he would put it on tinfoil and light it, and say he'd found my stash. It was beyond ridiculous. He accused me of cheating on him with everyone, of making him look the fool... When he was making himself look foolish. His accusations always came with beatings. My children saw their father turn their mother into a weeping, bruised, bleeding mess. I was an enabler. I paid our bills and did everything I could to make a happy home for our kids, and I was afraid to go to the police for help. Afraid of how hard it would be to fight him, to make him stay away. Afraid of the lengths he would go to to get even with me for leaving him... None of the things I was afraid of were scarier than him, in the end.
Cocaine turned him into an absolute raging monster. He broke all the windows in our home, shattered the door framed, urinated and vomited on the floors and furniture, tore all the photos and pictures from the walls, and broke every one of our dishes just to get even when I finally left and called the police. Not ONE day later he was calling from jail, depressed, trying to make up, trying to get money. He actually thinks I'd let him back in to the house... He never had a job in five years, and every dollar he made on drugs he spent on drugs or gambled away. He even took most of MY money, the money I used for the house and kids, to use on his habit and his friends. He was a worthless excuse for a human being, and I blame cocaine. I hate it. I hate what it does to people and their families. I hate the people who say it isn't addictive, and that it's fun. Yeah, that's right, I HATE YOU. Because you're making it ok for people like him to try it, to use it, to abuse it. Cocaine turns some people into killers. I don't know if it turns everyone into raving lunatics, and I don't care, if it turns even one person into the kind of man who would torture innocent people, and I'm a witness who will testify to that, then it's pure poison.

John McCain's picture

Coke

Just do coke once every couple months. Don't do more than 1 gram in a day. You will never have any problems if used in this way. If your weekends start revolving around coke, you are going to have issues. If you can't limit consumption to once every few months, then don't do it at all.

ART FULLEY's picture

a few mistakes

Hi,
A few corrections-beautiful story.art.

"Cocaine delivers an intensity of pleasure - and despair - beyond the bounds of normal human experience."
During the 1980s, Partnership for a Drug Free America began airing commercials that seem to either frighten or educate people about the use of illegal drugs. One of these commercials avowed, "No one ever says, 'I want to be a junkie when I grow up'." The comment is obvious, but very true. Probably very few people aspire to be drug addicts. But it happens, everyday. Why? What is so good about a drug that can potentially destroy a person's body? How does it work? What are its effects on the brain? Why is it so hard to quit?
Cocaine (C17H21NO4) comes from the leaf of an Erythroxylon coca bush. It is a drug that effects the central nervous system. It causes feelings of euphoria, pleasure, increased energy and alertness. People under the influence of cocaine often do not feel the need for food or sleep. They also feel energetic and may talk a lot. However, depending on factors such as environment, dosage, and the manner in which the drug is taken, cocaine can have adverse effects such as violent, erratic behavior, dizziness, paranoia, insomnia, convulsions, and heart failure to name a few. Long- term effects of cocaine include, but are not limited to strokes, heart attacks, seizures, loss of memory, and decrease in learning capability (1).
People may not always know the exact consequences of the drug they are taking, however, chances are that they do know that the drug is unhealthy for them. Schools across the country educate about the dangers of drug use and abuse through programs like D.A.R.E., television stations show anti-drug advertisements as a public service, and even city buses blazon anti-drug propaganda. People are aware that very rarely does anything good come from drug use, and still, everyday people fall victim to drugs. Why do people succumb to the urge to try drugs? It feels good...why else?
When a person takes cocaine, it causes a rush. There is between one or two minutes of intense pleasure. This is followed by five to 8 minutes of euphoria, then as the high comes down, an overwhelming urge for more, which may last for a day. (3) When a user is between cocaine doses or halts usage, the opposite effects occur. The user is depressed and tired (2).
Cocaine is attractive to users because it triggers dopamine. Dopamine is a neurotransmitter that is present in many regions of the brain. In normal mice, the introduction of cocaine increases dopamine by 150 percent. Dopamine regulates movement, emotion, motivation, and the feeling of pleasure. In a normal brain, dopamine is released by a neuron into a synapse and then it moves to dopamine receptors on other neurons. THE DOPAMINE REMAINING IN THE SYNAPTIC SPACE IS CLEARED BY DOPAMINE REUPTAKE RECEPTORS.
When cocaine enters the area of the brain where the dopamine is located, it blocks the reuptake pumps that remove the REMAINING dopamine from the synapse of the nerve cell. Thus, dopamine LINGERS at the synapse and feelings of intense pleasure result. This feeling continues until cocaine is removed from the system BY OTHER MEANS. (2). Research findings by the National Institute of Drug Addiction (NIDA) demonstrate that cocaine not only AFFECTS the level of dopamine in the brain, but also the level of SEROTONIN. In a study using mice without dopamine RECEPTORS?, the mice were given cocaine and they still experienced rewarding effects. This was obvious because the animals kept on attempting to get or self-administer more. These researchers speculate that more than one neurotransmitter is responsible for the pleasurable feeling cocaine yields (2). WE NOW KNOW THAT COCAINE AFFECTS dopamine, AND norepinephrine, and SEROTONIN RECEPTORS. some scientists report that cocaine AFFECTS approximately 90 different parts of the brain, not just the two main regions of the amygdala and the nucleus accumbens. However, it is interesting that it is these two regions of the brain that remain active after the cocaine has left the system, and the powerful, uncontrollable desire for the drug has set in. (3)
The first time people use cocaine and its effects fade, they want more. Such is the nature of the drug. The main reason cocaine use continues is the URGE TO RE-EXPERIENCE THE PLEASURABLE "high" and THIS LEADS TO THE development of dependence. Dependence is, "the need to maintain a level of the drug in the brain to both satisfy the need TO stimulate the reward center, and TO avoid physical withdrawal symptoms" (5). There is continuED research occurring about dependence and how it can be PREVENTED?
It was recently discovered through newer imaging techniques that cocaine hinders blood flow. This is why is it can cause brain damage or defects. Recent research demonstrates that if a cocaine user even thinks about cocaine, the blood flow is altered . This suggests that the addictive nature of the drug is stronger than we think, because simply thinking about it produces similar results in addicts' brains' (4). This is likely to be a result of the way in which cocaine changes the structure of an abuser's brain. For example n experiments done with lab rats, scientists reported that after repeated exposure to cocaine, the rats' dendrites changed by becoming bigger and denser. This means that an increase in synaptic connectivity results from cocaine use which triggers people and animals to work harder to attain the drug (6).
Scientists are working furiously for a way to combat cocaine addiction. They specifically are examining the genetic factors that contribute to the addiction (5). However, even if scientists do identify all of the factors that cause addiction, they are still faced with the dilemma of how exactly to stop the addiction. New hope to end cocaine addiction lies in experimental drugs, such as one that is used to treat epilepsy and holistic approaches such as acupuncture.
Although it may seem like science knows a great deal about addiction and the effects of cocaine, scientific knowledge still cannot make the cocaine problem disappear. There is no sure cure for cocaine addiction. Once you try the drug, YOU WILL BECOME ADDICTED. IT JUST TAKES A FEW TRIES. There is no cure for the addiction. SO, Before trying the drug, really think, is a moment of pleasure worth a lifetime of pain?

Eva Brooks's picture

Cocaine is no more addictive than love

But lucky you whoever you are!!! You could afford a cocaine habit for 10 or 15 or 18 or 20 or 26 years? Wow.. that meant you got very high for a very long time... and still you are complaining. Well, I am here to put in a vote for the side that doesn't get too many votes, The 'drugs-are-magnificent-parts-of-nature' side. I started using 'illegal' drugs when i was 14 years old and LOVED them... I spent many of my teenage years rocking out particularly on amphetamine, And then as a musician, moved to London, where, not only was amphetamine the most popular drug, but I met my boyfriend who later became my husband and he loved drugs as much as I did (and still do/does 35+ years later). We also both injected drugs for quite a long period, and then both stopped for different reasons. He went out to work on oil rigs in the North Sea and thus, smoked dope only for his two weeks offshore, as most of the men did as there was no alcohol allowed. For me, I would just periodically fly home to New York for a break in habit and have a personal health cleanse, and eat and sleep for a few months and forget completely about any urges to get high... it's that simple. Replace it with something equally enjoyable... food, sleep, a love affair. It's just, come on... let's get REAL: it feels THAT good, you never want it to stop... but then it does and you move on to something else. I stopped completely after about 5 years of injecting amphetamine (up to 7 grams a day) and to tell you the truth, I have no memory of why I stopped, except I moved to a new city (Amsterdam) and it was no longer part of my life. It was not in the least difficult, it really was just no longer a part of my life in a new place. Speed was a very 'London' thing at the time. So, end of the speed chapter. Eating and sleeping commenced. After that my recreational drug use was restricted to visits from friends from Great Britain who would show up for the odd weekend and we'd all get very high or drop some acid or take some Extacy as that was the new drug on the block. My drug use really dwindled to absolutely like 'none' over the next few years. I was a professional musician and I was pretty much what you'd call a health freak until I entered my 50's (yes, we're about to introduce the fully fledged 'adult right to choose' here) and moved to Tucson Arizona to take care of an ailing parent. Well, perhaps you can imagine the rest of the story. The introduction of an extremely handsome 22-year old Mexican Mafiosi coke dealer to my acquaintance and 'lover' list and WHAM.. for the first time in my life I was using cocaine. Why? Because it was there, and it made me feel good and I figured, 'you know what? I'm going to be dead some day anyway.. I want to rock it til it stops.' And for a year, that's exactly what I did. i could afford to. I had the money. Didn't have to steal or beg or borrow or inconvenience anybody else. I snorted great gear, 24/7 and yes, after a few months my nose got raw. I used to line my nostrils with medicated cream before I would snort my lines. I had a special table, where I would chop them out and say 'grace' and thank God for the high that was about to hit me. thank him or her or however many gods there are, that at my mature age, I could still have such fun and love it and enjoy it and not feel guilty about it. Then one day, I had to leave Tucson and I took my last line at 6am on the morning of my final departure. That was 2 years ago. I've not had a line since. I've not thought about it much as a great deal of sleeping and eating and getting chubby and healthy again ensued and I realized one very very very true and important thing that nobody here has mentioned. Cocaine is NOT physically addictive. And re: psychologically addictive? No more so than love. If you don't have it, you can do perfectly well without it, unless it is the ONLY thing that made your day worth getting up for. If it was the ONLY thing in the world that made you happy, then you will search for it everywhere. But it is not the 'bogey-man' of drugs as it is constantly professed to be. It was an incredibly pleasant way to spend a year of my life. End of story.... PS... I don't even drink wine... down the occasional beer, and I don't smoke or take pharmaceutical drugs, except Ibuprofen for a spinal injury. I do yoga every day, have a magnificent body and just had a full heart check that came out 100% great i.e. better than OK. My cholesterol is a little high because I LOVE cheese. Maybe Cheese will be the death of me. Just remember, you have to die of something. I think for most people who take drugs, it is the fact they really cannot afford them, they really have absolutely NOTHING else that gives them joy and they REALLY feel GUILTY taking them; these are the things that do the most damage over all. For those who go to jail.. .. what can I say, if all drugs were legalized that would not happen. I am an advocate for all drugs to be legalized and legally available to enjoy - without guilt or the sky-high life-wrecking prices of the mafia man. You could also monitor the quality, so it would not contain crazy chemicals that get chopped in to thin it out and do the most damage. Legalization is the only way to go. i won't even go into the roster of how many very famous people have lived on cocaine from Kate Moss to the Rolling Stones and how many Wall Street bankers made their careers on it. Legalize it so not only the 'rich' can enjoy it safely.

Robert  too much too long's picture

Round and round

Hi folks. I read most of the posts and want to thank everyone for their contributions. I started using cocaine as a teen 33 years ago I'm now 52 and have stopped using for 3 days. I've tried to stop many times only to return back to using cocaine time and again. Someone said its a weakness. I agree cocaine makes my brain sick and causes me to to make weak choices. Over the years as a result of my consumption sometimes as much as 8 grams in one night solo burning a pipe or snorting I've lost everything one line at a time except my life so far. I've felt like doing myself in many times the only reason I haven't is I tell myself it's better to use cocaine than to kill myself so I pick up and use leaving suicide for another day. These days I've lost all dignity. I'm getting old and I'm living off the generosity of my 80 year old mother. I'm on welfare and have redused my consumption to the limit of my meager income. That means I'm high for the few days at the beginning of the month and miserable depressed and useless for 3 weeks until my check comes around again. This is as bad as it gets. I spend most of my time alone In isolation to embarrassed to show my face or pick up the phone for help. I have a woman I love but I have t been able to do right. By her and she's now beginning to date other men. Ive been tring to stop using cocaine since 1990. I went many rehabs and joined 12step fellowships the longest I stayed off the drug was 3 years 7 months. There have been lesser periods of abstinence single years eighteen months six months and three months but not for a long time. I've been using regular for the last ten years. Im so tiered of living the way I do. I don't think I can go on much longer living in poverty sponging off my mother living in loneliness and shame. In the beginning of my cocaine daze there was money youth vitality ideas crazy sex and sex parties. Now 30 plus yeas later it's but a dream echoes of a life passed by. If I had my life to do over again the only thing I would change is to say no and refuse to snort that first line of pure Colombian my friend Dean smuggled into my country. In fact if I had known then how much misery it would cause me and my familiy I ...........
No Turing back now. One thing I noticed is that after three weeks clean I'm beginning to feel and be able to do a lot better. Also the scarey part is that I'm totally sober when I decide to put that first line in my body. Cocaine has been my biggest mistake in this life it changed my life for the worst.

Serendip Visitor's picture

Its funny how u. Said u can

Its funny how u. Said u can direct 2 dis one girl... Never is. Too late but do it wen u wanna live a lil while because u will feel dull.. I was in an accident. Dropped 30 feet flat on ground, dis was the only thing dat kept me from coma or dieing.. Have u seen the movie limitless.. Its on similar lines I think so, get married again have a child n leave it. To the responsibility.. I know u work in a balance but imagin ur highers u wud think u r on the same level but u shudnt be dere..what I feel I have become a very wise arogrant n dirty lil horny man

Serendip Visitor's picture

How to quit for free.

In my opinion rehab centres are simply not worth the money, and I've been through 4 programs. They extort your loved ones for money because they know that a loving family will gladly pay any price to get their child, brother, sister, etc off of drugs. Most places will claim a 90% success rate, but this is pure bullshit and is closer 30% based on my conversations with other fellow junkies in the programs who have also relapsed time and again. Remember, addiction treatment is a business first and they are mostly after profit - not your well being.

My last treatment at NARCANON cost $20,000 and only kept me away from drugs for the duration of my treatment. Once I was out I was hitting lines within a couple weeks. Plus they tried to convert me into some bullshit Scientology dogma - fuckin cult, fuck NARCANON! If you really want to pay the cash for rehab DO NOT pay these lying pricks!

Anyway, I successfully quit on my own and haven't touched cocaine for 6 months now (the longest I've gone for 10 years and going strong). All I did was call my friends who did coke and told them I was trying to quit and simply couldn't hang out with them - most of them understood except for one jackass and now former friend. Then I deleted all of my coke dealers phone numbers from my phone, changed my own phone number, and moved to a new apartment. It takes a little willpower but the philosophy behind it is simple: If you can't get a hold of it, then you won't do it.

It worked for me, and it was free. It may not work for everyone but if you seriously want to quit then try it. What have you got to lose?

I currently owe around $45,000 for all of my treatments as I promised I would pay my family back for treatment - which I am, and have been. I already paid off around $20,000. I just wish I didn't spend all that money on B.S treatment, especially NARCANON - fuck that place was a shithole (Trois Riviers, Quebec, Canada). I would have rather went to prison and got better food, and accommodation without spending $20,000.

PS: FUCK NARCANON!, and I WISH THE BEST OF LUCK TO YOU ALL!

Serendip Visitor's picture

Well done

Well done, I did the same as you and it works.

Serendip Visitor's picture

what i gained from crack, a mothers view

7 years in..... 1 and 1/2 out........ 12 years in = crack cocaine habit and the years in Prison you will have, not jail, Prison.
You started the habit at 19.... you are now out at 37 from all of this. No skills , no job, no family.No life.No social securioty to look for, you haven't worked to qualify. Now what??

No family or friends who will trust you ever again...like you maybe again..but no trust.

Still want to smoke crack?

I miss my son. I will never have the memories of his manhood growing up. He will never have them

Serendip Visitor's picture

Just have to reply to your comment

I am sorry to hear of your loss. I can imagine the pain and suffering through those many years. I am researching my own issues and came across your post and had this inner command to reply. At this point I just try to believe that in the end we will all be together again in piece and happiness. A better world where everyone is compassionate and loving. A place where sorrow does not exist, created by God Almighty. All we have is hope. I have been praying for guidance, health (mental and physical), Piece and love among all, forgiveness for my sins and special prayers for sufferers that I know personally. This has helped me cope for several years now.

Serendip Visitor's picture

Hi

I read your comments with sadness. I have had a similar experience and wanted you to know you had a compassionate friend here

Marie Wyke's picture

FANTASTIC

Melissa, first I would like to say....I read your report and it was excellent. I am a recovering cocaine addict with 18 continuous years clean and this is the first article I have read that was really on the money and not boring to read. As for Shane Skylar, let me advise you that you could use a meeting (NA) cause you are still using and second, go back to school with your illiterate behind. Shane, you really could use a narcotics anonymous meetings.......DRUGS ARE NOT YOUR FRIEND,...hehe. Look at what you wrote (see the part in Melissa's report, cocaine users talk too much). I'm just sayin.........

Serendip Visitor's picture

Getting Help is NOT hard

Lots of people on here are looking for help.
IT'S NOT HARD TO FIND...especially in Canada
You'll find help the same way you probably found this page....google
For some, it takes getting arrested (as i did)
I was forced to get help but it was up to me to find.
I still get urges but now have the tools to fight these urges.
I now know what triggers my urges and have been clean now for 4 months.
I was arrested for a half gram and the crown attorney was seeking jail time...FOR A HALF GRAM
Soooo not worth the risk
Stop now, get help. The people that truely want the help will seek it and will do well in treatment

Frank Johnson.'s picture

My cocaine addiction-Problem

I started doing cocaine as a performer playing guitar and then doing Karaoke at bar for approx 10 years. I would do it sporadically at guitar playing shows or karaoke shows as it would help me stay alert and awake during shows almost seemingly creating a "good show" due to my alertness and talking.. I don't know, but I began suffering from seizures in 2008. The seizures I had resulted after a time when I believe I bagan drinking beer (alcohol) again and got pretty messed up by having these seizures about the same time I started drinking...so I thought - and that's why I'm researching this topic....cocaine and the brain.....At first I thought that alcohol had everything to do with my seizures....But, I really do believe that the cocaine I did...which was regular at intervals...maybe 10 continuous days out of 30 days I would take it....but when I took it...I would take alot of it.....snorting whatever I could at times...between the cocaine rush.,,,,My seizures included my loss of short-term memory also...in fact, I did not even know what I had done for about 1-2 months! I even had a Karaoke gig, which I did pay-but was told that i was fired from the bar were i worked......so, my life at that times was insanity...to say the least.....well, i had a motor cycle accident in aug 2008 that put me into a 3 month coma.....almost died.....and now i live with tbi! for the rest of my life! so, was it worth the cocaine effect i got from snorting the stuff? Heck no!!!!So, my sporadic-prolonged usage of it may have caused my brain deficits.....is there scientific proof of the brain-neuron/cell damage and loss? if so where can I find it online?

Roy Boy's picture

Just a few words of truth

i'm 42 yrs old man and have been addicted to cocaine for 15 yrs+ at expense of my family.

Must of spent over 75% of my lifes earnings on it.

Things have fell apart around me, living a pretence to others, that things are normal, while really living in deplorable conditions.

Should of spent, that 75% of my life times earnings, on my children and enjoyed lifes natural highs and rushes, that millions of years of existence has blessed us with.

Its now time to change its never too late education is the key.

We have a tool available at our disposal, that previous generation had not.

The internet ... sites like this.

Use them to your greater benefit and free youself from your addictions as i'm no doubtly gonna do.

Serendip Visitor's picture

i want to STOP

All the info I've read touched me.I'm a31yr old wife&mother of4.i never used a drug in my life until january2007.like many other users the first time i did coke i LOVED it,oh yea my husband gave me my1st bump.turns out he has been using since he was15&i never knew..an when it came out i told him i'd rather him do it@home with me(not realizing thr effects it would have on me)i don't like the way it makes me feel anymore. Its almost like i can feel my brain sweeling cuz when i get too high all i feel is pressure in my head. I have uncontrolled movements..like twichin or tremors.an my nose i just gone.i was bipolar before i started doin coke,an i dint feel smart anymore.I'm forgetful all the time.it doesn't seem to affect my husband at all.i be so high i feel like I'm about2die rite at that moment as if my brain about to explode.i realize i only feel those effects if i try to do more tgan2.5grams..having said all that,i still do bumps every time he passes it to me.God give me the strength to help me stop.i haven't moved up2coppin my own,si basically the only time i get hgh is when my husband comes home wut some.so we do3grams a week someone please tell me is that alit?dam i beed help!

I HAVE TO STOP IT TOO's picture

i want to stop

I know what you mean... I use to have girlfriends and we did it together, then sex was crazy, but fun at time,... I went through alot of money... I borrowed yet its been 6+yrs. I do maybe 3 times a week but when i do... I do about 3-4grams in spurts overnight... Then i need more.. I already have anxiety disorders and was bpolar no need to sleep when i do... but when coming downm its depressing... Also this has been hidden from my entire family. Seems like something is up to them i think.. But they dont know... It all started i use to buy big stuff 8balls, 16ths, quarter oz's... my friends got paid they came paid me money... So it paid for itself in begining... Now as time went on I became a loner a closet case. In beggining i use to suck through my mouth to keep numb.. But that first bump i mean bump like a rope.. I loved it. Sex was alsome... I dont like paraanoid feeling but sometimes I actually start to fall asleep like opposite affect, like if i took a bump, id lay o couch.. fall out like a light... my buddy said chris i put 2 more up. i wake up take it get that great drip and talkitive happy feeling. WHEN THE COKE RAN OUT, I COULDNT DEAL WITH IT... IS THERE SOME FREE HELP OUT THERE IM IN USA/ PHILA PA area... Because i want to quit im ready i need my life back... And wanna love my family again normal.. I changed i look in mirror and know i changed for the worse, but i go back for more....??? See i wanna help myself but sont wanna tell family about the addiction. please email me any sources thqanks alot sincerely
chris

Serendip Visitor's picture

Sounds all to familiar...

Chris... Your not alone in what your going through. I really think Coke effects everyone differently depending on so many factors (like brain chemistry) also what starts out as a fun social drug can progress into a chronic habit that makes you want to lock yourself away from the world for hours & days at a time ... Until the drugs are gone!!
The hardest part is to break the cycle your in. Trust me I've been there! You don't Have to wait for someone else to confront you about what's going on.
Maybe you think you need someone to tell you that you have a problem... Time for rehab... Stop stealing my jewelry .... YOU know it's time to stop. Rehabs probably great but it's not the only way to get off drugs. If you've got loot for 8balls you've got money for a therapist someone to talk to.
The problem is the drugs and people who use them are ALL around you.... I'm in Philly to but it's not about Philly it's about who you know and hang out with here ... You need to stop for a while to start feeling better and get perspective and your routine where you are now is going to make that really really difficult.
Best advice I could give you ... Move away for a while! I mean far away. Get a job on a cruise ship, move to a ski resort in Colorado, move to the Bahamas or any carribean island ... Get a job at some big tourist resort... Find a room for rent on craigslist and tell your parents your going for 6 months a year to check it out ... You won't know people in the drug scene in a totally new place so unless you seek it out drugs won't be in your face all the time.., (just DO NOT work at a bar!!)
Philly sucks anyway... Especially when your locked in your room doing lines all fucking night alone! Give it a try man, what have you got to lose?! Could turn out to be thd best decision of your LIFE!
Good luck man
Noodles

frank johnson's picture

reply for want to stop!

You have got to stop yourself now! If you don't, you may end up like me with traumatic brain injury and be disabled th rest of your life....and once that happens.....you won't have any more choices.....like me....I used to be a pretty-good musician....played guitar pretty good, and fast...and I could sing too....now I can't do either good at all....my problems are in my comment I left earlier on this site...read it when it comes out....Not a lie also.....Keep on doing the stuff...you may wake up one day like I did...out of a 3 month coma! and intense brain damage! I still have terrible short-term memory.....and lost about 15 years of long-term memory from neuron-cell damage/loss...."is this want you want to be too?" well, keep on snorting those "bumps" as we call them....do you have children? well I know they probably love you very much....you are going to put them thru emotional suffering from loosing their mother....or who she was before she became "brain-dead." oh, and i'm sure you'll hear all your coke-friends tell you-it's okay....only some people get hurt sometimes from coke....mostly if they shoot it up....that crap! it kills brain cells after prolonged usage....gauranteed....wanna prove that right? Keep on doing your bumps! You'lll find out! so, quit the snorting NOW!!!!okay? or live a life of having an almost "dead brain" see how you like that.....

jf's picture

coke is death

I've been a addict for over 8 years. The first 3 years it was fun and I felt like this would never affect me phisically or mentally. Now I'm 27 years old, my nose is damaged,I'm always tired, sad afraid of any social situation,very deppresed. DON'T EVEN TRY. But I have great parents,brother and sisters and acouple of people I would consider friends and they give a lot of support. I don't want to let them down so I quit couple of weeks ago and hope for the best... I know god will help me

Serendip Visitor's picture

You better stop why you still got the chance.

The first time I tried it was about a year ago now. I was at a friends going away party for the military, and I had been offered coke before then but was to nervous and scared to do it. I had been smokin weed for about 3 years before the first coke use. I dont really think weed is a gate way drug in the sense that you want another high. The high that you get from weed is uncomparable to any other drug,even pain pills. But I do think we is a gate way drug in the since that it takes you one foot in the door with the drug world and drug use. But my first time, the feeling was unexplainible. LIke everybody says, its a verry good and pleasurable feeling. But I promise that the first high you get from cocaine and you like it, that is the beginning of the hill. And its straight down. I didnt do it for a couple of months after the first time, beacuse I got it threw a friend. But when I met my first connection which was only a few miles from my house, that was the moment my life went hay wire. I used every few weeks, then every week. then every few days, and now after almost one year, I have gone on two week use. Cocaine was made in the palm of the devils hands. It will set the bait, and once you take the bait and like it, youre in for at first, what seems to be good ride, but at the blink of an eye, your comedowns are so nerve racking that you feel like somebody is watching and listening to your every move. And for me when I would comedown i would hate coke soo much I would swear to myself that I was done with it. But beacuse of the addiction after I camedown and got some sleep, I wanted and went and got more just like before. Im still struggling now, but I have noticed that my chest hurts when I use now. I used to somewhat enjoy the use of it even a few months ago, but its now at the stage where maybe the first line and drain, makes me somewhat feel good, but after that, it sucks. But because of addiction you keep doing it, and telling yourself the next line will be better. PLease just stay the hell away from it. Look at charlie sheen

little one's picture

Im only 14 years old... with

Im only 14 years old...
with a normal home, im still all alone
cocaine gave me a crave.. took my soul to the grave and left me here to wait.
is 8o bucks a gram really worth the after pain that still stands.
I guess its all i know
pot was gold
coke was as beautiful as snow
now it melted and turned to brown
heroine and crack turned around
stabbed me in the back
now all I have is regret

Tim's picture

Huh

80 bucks a gram u got ripped. I pay 40 for the fire

Serendip Visitor's picture

Death by cocaine

My son died last summer from cocaine addiction. He blew his head off with a shotgun. I found him. He was my first child and only son. He was 33. There is nothing I can say to you to make you stop doing cocaine or other drugs. But just know, that when you die from them or suicide, or if you are mentally incapacitated from doing them, your family who loves you will have to live on and endure the pain of losing you to drugs, for the rest of their lives. It's one thing to kill yourself, but another to inflict that kind of grief and pain on so many others...

Just a little help's picture

I am dreadfully sorry for

I am dreadfully sorry for your lost. I pray that you will find some peace and that your son is now wrap in the arms of the true God, Jesus. I ask everyone out there to say a prayer, rather if they DONT believe orDONT feel like it, for one week three times a day. They must kneel, it doesn't matter where and women must cover there heads as they pray. Starting, 11-22-11. Cocaine, crack, refers, and cigarettes addicts. PRAY LIKE YOU NEVER DONE BEFORE. DONT GIVE UP.

frank johnson's picture

I'M SO SORRY ABOUT YOUR

I'M SO SORRY ABOUT YOUR SON....AND I KNOW YOU MISS HIM TERRIBLY, BUT YOU CAN REST ASSURRED, HE IS IN A BETTER PLACE...WHERE NOTHING CAN HURT HIM ANYMORE....I PRAY FOR HIM, AND FOR YOU TO FIND CONTINUED STRENGTH IN LIFE....I HAD A SISTER KILLER HERSELF WITH A HANDGUN SHE WAS USING TO BE A POLICE OFFICER. SHE SHOT HERSELF, BECAUSE A WOMAN SHE WAS INVOLVED WITH (SHE WAS LESBIAN) LEFT HER....SHE COULD NOT TAKE THE SEPARATION AND SO KILLED HERSELF ONE NIGHT...I WAS STATIONED IN GERMANY IN THE ARMY WHEN I GOT THE CALL....BUT I KNOW SHE IS IN A QUIET-PEACEFUL PLACE-AND YOUR SPIRIT LIES CLOSELY TO HIM ALSO....HE DID NOT DO IT TO HURT YOU....HIS ADDICTION TO COCAINE BECAME HIS HELL IN A PLACE WHERE LIFE CAN GET SO HURTFUL SOMETIMES.....HE IS IN PEACE.....WHERE HE WILL BE WITH YOU ONE DAY....AS I KNOW I WILL BE WITH MY SISTER ALSO. OUR SPIRITS BECOME A "ONE" IN OUR SPIRITUAL LIFE....THE LIFE AFTER THIS LIFE IN THE "FLESH"....THE FLESH BEING THE HUMAN-FORM WHICH WE EACH LIVE IN THIS EARTH....I PRAY FOR HIM AND YOU.....GOD IS WITH YOU AND HIM (AND ME TOO!).

Serendip Visitor's picture

Living and loving among coke.

I personally tried coke when I was 18. I worked at the bar and briefly dated a coke dealer. It was an interesting experience but I had bigger ambitions and I stopped and moved on with my life. I never returned back to thoughts about trying any drugs. Almost ten years later I started dating e a coworker who had drug problems. He is a nice guy. He has a good heart. However coke and other drugs that he have used through out his life (for about 14 years) have really affected his mental health. He is bipolar. He admits to that. However he does not admit that it is from drug abuse. He blames it on genes because his mom was a heroin user prior or during her pregnancy. He have used any imaginable drug out there except for heroin (he is scared of it, especially because him mom was an addict). I dated him for almost a year. It was really hard. He also smokes weed daily. He did not mind me smoking on occasion. However he would never want to do coke with me. He was telling me that I was too pure and he wants to keep me that way. Eventually we broke up but because of his mental irregularity and altered feelings he keeps calling me back. If I meet him he is happy and emotional. However if I show up without warning he freaks out and goes crazy. He does not want me to see him with other women or on drugs. I've tried to help him so many times and he have tried to stop abusing drugs so many times but every time he fails because he gets depressed and lonely. Then he goes out gets drunk and finds a bad company and bad girls that are ready to party. If you tried it and you liked it don't do it again... Don't make it in to a habit. If you haven't tried it don't go that rout... It's not worth it. Drugs really mess up your thinking, emotions and feelings... It's hard to get away from drugs once you are in...

Jim Johnson's picture

Nice post

I read your post. Thanks for the insight. You've made me rethink my path.

Thanks,

Jim.

love drug's picture

haha

seriously the drug isn't anything like some of these comments have said.. maybe if you have grown up around nothing exciting, you will find that cocaine is the best thing thats ever happened to you.. i however have been snorting at least a gram a day or more for two months now and the only problem i have is my fucken nose hurts at the end of the night. if you really find it that hard to go a day without it then you are a fucken weak minded piece of shit who deserves to be addicted to it. i've recently quit smoking weed because i realised that i had been stoned for 3 years straight. i'm 17 and i see my friends smoking everyday and feel sorry for them. if you really want to quit (anything), it takes 3 days and the cravings go away, then you feel your old self start to come back, and all it takes is you saying to yourself "ahh actually thats right i was coked for two months straight, i think i can go sober for a week" whatever the drug may be, if you cant ditch it, for a week at least.. who do you think you are? your a fucken nobody.

Serendip Visitor's picture

Sorry- You say a gram and a

Sorry- You say a gram and a half a day and the only side affects are that your nose hurts? If i was you i would ask for a refund as it sounds like someones been selling you something that "isn't coke" and I'm sure that will be messing around with your insides. Just because you cant see/feel the side affects dont assume you are not having any.

Every one is different. some people CAN take coke and not get hooked on it, some people can take it or leave it. others can get hooked after one/2 goes and others might have been doing it for years thinking "they dont have a problem". notice the doing it for years? prob a sign it is a problem.

Some people may do a line and be buzzing and feeling great- someone else may take their own life. why take the risk? why do we risk our precious lives? I dont know and I cant answer that. I'm one of the people that can seem to take it or leave it. I've never craved it. but one thing i do know is life is to precious to waste it on this. get another natural high that wont risk your life, or affect your moods or your friends and family.

perhaps if everytme we went to do a line and there was a post it next to it saying " this could be the last thing you will look at" we would think again.

to anyone that has lost anyone from drugs i send you my heartfelt condolences.

Tim's picture

Woh woh woh. Take there own

Woh woh woh. Take there own life from a line. Ignorance is bliss.... Remember that. Are you one of the people telling our kids weed will kill you. Coke isnt really a problem in moderation. As they say in the 20s when it was legal a small few would start a habbit that effected there life. I wish the coca plant was legal.... Hopefully soon it will be. It has so many health benifits and people knock it down cause you can derive a stimulant from it. Who cares. It isnt the end of the world. I wanna put my 40 hrs in, and dont worry my yearly net is way higher than your gross, sit back have a few beers and blow a line, who cares. And if u think about it the alchahol impairing my judgment and reaction times while the cocains making me more alert. Whats worse for you

Lance Collins's picture

I;m nineteen and have been

I;m nineteen and have been doing drugs for three years. For me it started with pot which was pleasnt until i started doing more and more until i was fried everyday. Mainly just killed motivation. I moved on to cocaine, and stayed on it a full year. I snorted probably four grand worth in a matter of a few months and then began shooting it. i then shot roxies for awile and tried many diffirent drugs. Shrooms, 2ci,2bc, lsa, meth, any opiate besides herione, embalming fluid, crack, ecatasy, bath salt, daylights molly (pure mdma). I shot up until four months ago, from my experience there are three diffirent kinds of shooters. One who tried it, hated it and will never do it again, the next one tries it, loves it and will forever do his drugs in that manner, or me who tried it liked it but all in all it was just another method. Cocaine has been the worst and only drug i used for a prolonged time. The side effects are easy at first but they eventually become more intense and harder to cop with. I will say that my brain has been damaged, i am a borderline socio-path and was that was not the case before hard drugs. Which is horrible becasue they are the only thing that makes me feel emotion anymore. Drugs have wrecked my life so far. If you ever start or wanna start think about this, you do the drug and hate yourslef for doing it, then you detox, shit and puke, dissapoint the people you love, wait all day to deal with some mean big aggerssive peace of shit, and damage your mind and body even with small use. People..... We spend our money to destroy everything around us including ourselves. If anyone can tell me one good reason to do drugs please by all f'n means speak up, but chances are, your just going to be justifying your addiction. Take it from a professional junkie, quit, by any means you can. Im joing the army and have been clean for two weeks off everything. God help me to correct myself.

Serendip Visitor's picture

Seriously lol

Who do you think you are?!? You go around and feel sorry for the people smoking grass when your sitting there putting "chemicals" right up into your nose for more than two months straight. You are not in the position to pass judgement on anyone. I think you need to take a look in the mirror pal and realize you shouldn't hand out criticsm of any other human being when you yourself have issues, just like everyone else. How were you blessed to be so almighty that you can go around saying people "deserve" to be addicted and they are "fucken nobodies"? Read a book or do some online research and tell me what you find out about it only taking "3 days" to come clean and return to normal. On that note, i'm not even sure why I am replying to your incredibily stupid post but it seems to my that you have a very closed mind and you should look into talking to someone about your situation.

Serendip Visitor's picture

Um..

You say you snort at least a gram a day or more...and say people are weak minded when they're hooked on it. So i guess you're weak minded there. And good lord your grammar is painful to read.

Serendip Visitor's picture

Ignorance is bliss

Then I'd say you're getting some low grade powder, and I'd also say that you haven't really experienced a solid coke high as a result. Here's a little tip for you kid, if it tastes like baking soda...it likely is... LoL.

The post I made earlier was regarding my personal experience with 'caine. I really don't care if you learn from my mistake or not. Hopefully someone else will.

Use 'caine if you want to, but don't waste my time again with your ignorant reply.

Serendip Visitor's picture

The all mighty powder.

I've been using coke for nearly 10 years straight since I was 17 at about 2-3 grams per day. From my experience I can say that the first few years were the best of my life. The high of 'caine is amazing and gives you unbelievable feelings that are seriously indescribable unless you try it.

After that it's all downhill. You try to get that same high evertime and it begins to be a chore and a routine more than anything. So you end up using more and more at work, at home, with friends, and everywhere else. Trust me there's nothing good at the end of the road. Before you know it, you look older, you feel depressed, your body starts to complain, your mind isn't sharp anymore and life begins to really suck.

I'm not preaching crap to anyone, try it and use it if you want and you'll experience some kick-ass times. But in the end the powder will win and eat you up inside and out. It doesn't matter who you are.

I have a masters degree, I used to work out daily and you wouldn't recognize the changes it can do mentally and physically until the changes creep up on you, and then bam you realize it's time to quit.
I've stopped using daily and now use once monthly. Baby steps I guess... but I will kick its ass before it kicks mine.

Karen's picture

I'm 48 and am a business woman

I'm 48 and am a business woman and very respected in my community. And yet I have this dirty little secret! :(
I feel really bad because I had been clean for about 10 years and thought I could handle it. Because I was older and smarter, Well guess what I might be older but certainly not smarter. And my use has gotten worse. Sometimes I'll quit for a couple weeks and it calls my name. I don't remember powder ever being so powerful. But here I am still trying to kick the habit once again all these years later. I'm 48 and have been using again since about 05 and swore at the beginning of this year I was done. Here it is almost July and I'm still struggling the worst part about it is this time I took my beautiful 30 year niece with me. I told her the same thing you said baby steps. We are starting to make bets and deals with a payoff. We use together 2 to 3 times a week we only split a 50 in most cases. We both want to stop desperately before its too late! Just thought I would share our story as I'm sure your not alone, I plan on kicking its ass as well and yes she's coming with me! ;)

SMOKING HOT FILTHY RICH LOSER's picture

STOP!! NOW!

I am a smoking hot girl in my 20s, come from freaking rich family, I myself am a millionaire, can do anything I want whenever. Was always very successful and intelligent, went to the best colleges... best jobs... blah blah. Started doing IV coke for a few months in 2004. It screwed up my brain so bad I have SEVERE depression, mood swings, nothing, NOTHING makes me happy, I binge eat, can't keep a relationship, can't hold a job. My life has been ruined. I stopped doing the coke 7 years ago when my parents found out and helped me stop. But the damage it did to my brain was so severe no one can help me now. Doctors have me on tons of meds but I still end up in the psych hospitals about twice a year for suicide attempts or horrible depression. My life will never be the same. I beg you to realize drugs DO fry your brain. Plus I don't think I am as smart anymore. I FEEL dumb, like things are harder for me. I used to be a genius. Just something to think about. Putting it out there to help at least one person.

Serendip Visitor's picture

Smoking hot filty rich loser

Do you still feel the same?

Rob from london's picture

To smoking-hot

Ditto there, Ive just crossed into my thirties, I've had a good life, but... I can't shake this habit. 2-3weeks a month I will get through about a quarter a week. After every session I despise myself and pray for the strength to not go back. It's spiralled over the last 5 years and now like you say I feel more and more stupid. I can still do the things I used to be able to but only just and it's a case of motivating the right brain cells. The really sad thing is that no-one ever reads these blogs/advice pages until it's too late. A teenager can prepare for sex for the first time as it's inevitable through natural desires. But no-one actively goes out to destroy their mind and body by researching first. I'm sorry to hear that you are on meds now. God knows what's down the road for me

yvonne hiller's picture

STOP!! NOW!

What a heartbreaking story this was, makes want to weep! But all is not lost, you can still have a good life and that life could be spent helping others. Also, I would encourage you to seek after God, the bible says that if you seek him with all your heart he will come to you. I pray that this will happen to you and that you would become a "new" person and that you would come to know Jesus Christ as your personal saviour. I am so touched by what I just read that I am weeping. Love in the name of Jesus Christ, King of Kings and Lord of Lord!!! Amen!

Serendip Visitor's picture

Never knew until I thought about it and did research

It was a Friday night .I was sitting at the computer and I heard alot of people outside .I didn't have any friends around my neighborhood mainly because I'm new around town.So I decided to go outside and talk and maybe meet some new friends to hang with for the moment. I smoke weed so I ask them did they have any(but I dont smoke weed often).One of my friends I wasn't too sure with ,said he had some weed ,he said "follow me " so I did.

I went in the house with him and he had some weed. But when his friend who was a girl walked in , she notice that my friend had something in his nose and she tried to clear it for him(it was coke).He ask me did I do any other drug besides weed such as coke and I told him "NO".I'm not sure if he knew if he still had some coke on his hand before touching the weed,but after smoking the weed .I decided to leave .

Once I got home I noticed when I swallowed some juice I had pored,it seemed as if I had something in my noise . As time goes by , I felt some type of way ,I stood up and went in the bathroom, I felt so horrable .Its like I never felt this way off of weed a day in my life. So I was looking at myself in the mirror and desided to talk and negotiate with myself if I should tell my friends back home the story ,because I felt like such a coke head and it wasn't even a large substance of it .(My friends doesn't do coke and neither do I, thats why I was alittle wierd about telling them the situation ).

I then went back on the computer as if nothing had happened feeling alittle more happy and started to feel like the high went down and felt like I smoked weed. (I DONT KNOW IF COKE WAS INVOLVED ,MAYBE A LITTLE GOT ON THE WEED FROM WHEN HE DID THE COKE EARLIER BEFORE I GOT THERE , BUT IT WAS THE WORST FEELING EVER IN MY LIFE).

I continue to hang with my friends but they knew I didn't do any other drug other then weed. They had some weed I smoked with them again and it actually felt like I smoked weed. I FELT SOME TYPE OF WAY SO I DESIDED TO do some research about coke.That explain why I am on this website today.My emotional behavior seem like the cokehead stories on this website. And out of the research that I've done ,maybe there was a mixture of drugs that day .I WOULD NOT WANT TO EVER DO COKE IN MY LIFE, IT MAYBE GREAT FOR OTHER PEOPLE , BUT ITS NOT A GREAT FEELING TO ME ,I GUESS THAT DRUG IS NOT FOR ME AND I DONT WANT TO BE ASSOCIATED WITH THAT DRUG AGAIN.(Haven't smoked weed since , I just been having mixed feelings,maybe I shouldn't do that drug either.)

Serendip Visitor's picture

Fibromyalgia

I was diagnosed with fibro 5 years after i quit a 4 year binge. studies need to be done on this subject. i currently take 9 medications most for pain one for bi-polar, and two for sleep. wanted to share this

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