The Effects of Hallucinogenic Drugs on The Brain

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Biology 202
1998 First Web Reports
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The Effects of Hallucinogenic Drugs on The Brain

Alicia Ebbitt

Hallucinnogenic Drugs alter a person's perceptions of reality and may cause hallucinations and other alterations of the senses. Drugs classified as hallucinogens include: LSD (lysergic acid diethylamide), 2,5-dimethoxy-4-methylamphetime(DOM), N,N-dimethyltrptamine(DMT), psilocin, and mescaline. There are two aspects of these drugs that classify then as hallucinogens. They all have common side effects, including distortion of sensory perception, and other psychic and somatic effects. These drugs also exhibit cross-tolerance. This means that a user of hallucinogenic drugs develops a higher tolerance to hallucinogens, the more they are used and the shorter the time span is between the last usage.

Hallucinogenic drugs have been used throughout history for a number of reasons. They have been used as medicinal agents as well as having served religious purposes. Hallucinogens such as mescaline have been used in Native American ritual ceremonies. There was extensive usage of hallucinogens in the 60's and 70's as part of the counter- culture hippie movement. During the "acid tests" of this era, hallucinogenic drugs were used for mind exploration (B.L. Jacobs, "How Hallucinogenic Drugs Work").

Hallucinogenic drugs cause both physical and psychological effects on humans. The physical effects of these drugs include: dilated pupils, elevated body temperature, increased heart rate and blood pressure, appetite loss, sleeplessness, tremors, headaches, nausea, sweating, heart palpitations, blurring of vision, memory loss, trembling, and itching. A user of hallucinogenic drugs will also experience a number of psychological alterations in the brain. These drugs may cause hallucinations and illusions as well, as the amplification of sense, and the alterations of thinking and self-awareness. It is quite possible to have a bad reaction to hallucinogenic drugs. This is referred to as a "bad trip" and may cause panic, confusion, suspicion, anxiety, and loss of control. The long-term effects of these drugs can be quite dangerous. These long-term effects may include: flashbacks, mood swings, impaired thinking, unexpected outbursts of violence and eventually possibly depression that may lead to death or suicide.

Quite a lot of interest concerning hallucinogens has been generated by neurobiologists and other scientists. The effects that hallucinogenic drugs have on the brain are quite complicated and very interesting. Many users of hallucinogenic drugs have experienced whole personality changes which raises questions about the relationship between brain and behavior. Scientists are also curious as to how total alterations of the senses can occur as the result of hallucinogen usage. Many people that have used hallucinogens claim to have "seen sounds" or "heard colors". Scientists ask questions such as: How can a person under the influence of hallucinogenic drugs see things that aren't there? or How do flashbacks work? Another aspect of hallucinogenic drugs that interests scientists is that they are psychomimetic meaning that they mimic certain aspects of psychosis. Through the use of hallucinogenic drugs, one can induce temporary symptoms of psychosis.

As a result of the great interest in hallucinogens, many years of research have been done to try and determine exactly how the brain is affected by these drugs. Scientists have tried to determine if there is a specific site in the brain where hallucinogens act. This has been difficult to determine. Scientists still are unable to answer all questions about hallucinogenic drugs. However they have been able to determine certain areas of the brain that these drugs do act upon.

Early on in the reasearch on hallucinogens, it was determined that hallucinogenic drugs structurally resemble serotonin (5-HT) Serotonin is found in specific neurons in the brain that mediate chemical neurotransmission in the brain. Neurons containing serotonin can be found in the brain stem section of the brain. Axons of serotonergic neurons project to almost every part of the brain, affecting and communicating with all sections of the brain. Serotonin also acts at many receptor areas of neurons. Because hallucinogenic drugs are structurally similar to serotonin, it was theorized that hallucinogenic drugs may act upon serotonergic neurons (B.L. Jacobs, "How Hallucinogenic Drugs Work").

Scientists began to carefully study the serotonin system and found out that hallucinogens do in fact have some kind of effect on serotonin. Hallucinogenic drugs cause an increase in the level of brain serotonin, but they inhibit the rapid firing of neurons containing serotonin. This is a negative feedback system in which as the serotonin level rises, the activity of serotonergic neurons decreases. It was originally theorized that this effect of hallucinogenic drugs directly caused sense alteration and hallucinations. Several observations however have shown this theory not to be true. These observations include the following: Low doses of LSD effect behavior, but do not depress firing of serotonergic neurons, The behavioral effects of LSD outlast the alteration of the firing of the serotonergic neurons, Repeated dosage of LSD results in a decrease of behavioral changes, but still effects neuron firing, Other hallucinogens do not affect serotonergic neurons, When serotonin levels are depleted, the effectiveness of LSD is not eliminated (Ian Leicht, "Postulated Mechanisms of LSD").

It has now been determined that the effects of hallucinogenic drugs are actually caused by the effects that hallucinogenic drugs have on the post-synaptic activity of serotonergic neurons. Hallucinogenic drugs directly affect the serotonin receptors(specifically the serotonin receptor subtype, 5-HT2), which is what eventually results in a complex pattern of action potentials and activity. This was proven by the fact that the depletion of serotonin levels in animals does not result in a decrease of behavioral effects caused by hallucinogenic drugs (B.L. Jacobs, "How Hallucinogenic Drugs Work").

Hallucinations and other effects of hallucinogens are however very complicated experiences. They are not simply a part of a cause and effect system in the brain, where hallucinogenic drugs act on serotonin and cause hallucinations. Instead, hallucinogenic drugs act initially on the serotonin system, which sends into motion, a pattern of complex action potentials and activity. Other neurotransmitters may be involved in these activities as well. The effects that inputs and outputs have on each other in this system as well as the pattern of action potentials mediated by hallucinogenic drugs help to cause many of the complex changes that allow hallucinations to happen. (B.L. Jacobs, "How Hallucinogenic Drugs Work") Scientists continue to do research to determine the exact effects that hallucinogens have on the serotonin receptors and to answer any questions that they cannot yet answer.

 

WWW Sources

1) NIDA (National Institution Drug Abuse: LSD(Lysergic Acid Diethylamide).

2) Hallucinogenic Drugs in Psychiatric Research and Treatment: Perspectives and Prospects.

3) Tryptamine Hallucinogens and Consciousness.

4) Hallucinogens (PCP, LSD, etc.).

5) Narcotics, Dangerous Drugs, and Marijuana.

6) Healthguide Online: Substance Abuse: Hallucinogens.

7) Hallucinogens.

8) Los Angeles Police Department Drug Recognition Expert Unit: Hallucinogens.

9) Postulated Mechanisms of LSD.

10) B.L. Jacobs. 1987. How Hallucinogenic Drugs Work. "American Scientist". 75:385-92.

11) M.C. Bindal, S.P. Gupta, and P. Singh. 1983. QSAR Studies on Hallucinogens. "Chemical Reviews". 83:633-49.

 

Comments made prior to 2007

When you list the drugs in the beginning of your article you list lsd psilocin and mescaline. But "psilocin" is not actually the active ingredient in hallucinogenic mushrooms. The correct term is "Psilocybin". Just thought I'd point that out ... Daniel, 19 February 2007

Comments

Serendip Visitor's picture

LSD, tripping

After reading several pages of comments here is my 2 cents. I grew up in an unhappy home, and left when I was 18. I was attending a local university and met a man, a master manipulator, and I was trapped and the relationship was a constant torment for 5 years. One night he brought some LSD home and we "dropped acid", as it was called back then. Wow!!! Blew the top of my head off. Except for the asshole boyfriend trying to freak me out, it was a wonderful experience. I learned that I am part of EVERYTHING, and I saw that EVERYTHING is connected in ways that we cannot imagine. I started to block the boyfriend out over the years, but every time we dropped acid I had a wonderful experience. I "spoke" with GOD and I can tell you that GOD is not a person, not female or male, not anything. But, GOD made everything and everyone and GOD has absolutely no connection to what is in the Bible. Hell does not exist except in your mind. When we die we all go to "heaven", if you want to call it that -- really where we go is back to GOD and it is the most wonderful feeling in the world. I wish I could tell you about all the wonderful things I learned during my 4 years of tripping. I also took some mescaline and some mushrooms, but LSD was always my favorite.

Proper mental preparation is key to a productive experience. My attitude was that I was going to connect with the wonderful, with nature, and I learned that life is a wonderful trip -- no pun intended -- but lots of work, but work that is worthwhile. We are here on earth to make ourselves better human beings, we are here to love each other, we are here to experience something that we cannot experience when we are with GOD. I never had any flashbacks, although I found that I could remember what I had experienced on my trips and I could willingly see the energy fields around people, around plants, etc., and it is not scary -- it is wonderful. I also learned to do yoga from Shiva during one of my early trips and since, at the time Yoga was just being discovered in the USA, I have been able to attend yoga classes on a regular basis for the past 35 years.

For people with unhappy homes, I recommend plenty of exercise to release the natural endorphins in the brain, and I recommend finding a good yoga studio and learning as much about yoga and practice yoga as much as you can. Yoga will help a person get grounded and see that we are all one and destructive behavior will stop. We are each responsible for our own behavior, and the people who are jerks know they are jerks -- it is their path and if they want to change that path, then they, and they alone, will have to change. NO amount of prescribed medicine will change that.

For some who seem to have mental problems after a trip -- get help from a psychiatrist. My horrid boyfriend who first introduced me to hallucinogens had his first psychotic break when he was 29 and I thought maybe that would happen to me too, but then I realized that it was in his genes. His mother was schizophrenic and so was his grandmother, so there was probably no way he would not be schizophrenic. It was an experience.

Also, for people who are young these days, think about your diet. What we eat today is radically different from what I ate as a teenager. Stop eating processed food. Try to eat as low on the food chain as you can. That means fresh vegetables, fresh fruit. No Cokes, no McDonalds, no Burger King. Start growing some plants if you live in an apartment, if you have a yard start your garden. Get outside and see what GOD has created and enjoy!! Stop thinking about yourselves, stop being selfish. Think about helping your mom or dad around the house. After all, you live there too, and you will be happy if you help your parents. To the people in abusive relationships -- get some help and follow through with getting away from the manipulation and anger and control.

If you take hallucinogens please realize that they are not recreational drugs. They were created by GOD so that we can spend time with GOD, so that we can see the wonder that is our planet. The drugs are not meant for partying. They are serious business and cannot be approached with less than pure intentions. Taking drugs to escape the miseries of life is a waste of time and is nonproductive.

A very good book about LSD was written by STANISLAV GROF, MD, PhD., and he has some very good experiments in his book. His theory was that we could reshape our personalities and heal our wounds through proper use of LSD. I believe he is right and that is what my trips were about. I reshaped my personality (threw out all the negative things that I had been told as I was growing up) and started on the path to becoming a whole, loving, productive human being.

Peace and Love,
Robin

Serendip Visitor's picture

Just a little afraid of what might happen....

I'm little afraid of what might happen when my boy friend who will be taken shrooms for the first time. I'm very supportive of what he wants to do but after reading the long term effects it scares me. Wha5 if he one day forgets about me or something important or forgets when he was born etc. I just want some reassurance that everything will be ok because I askk him questions just to learn more about it he answers with I don't know and leaves it at that I would feel better if he just says hey there will be side effects with what I'm taking but it's going to be all right.... I just want some one to reasuure me that it wont be as bad as they say when he takes it again. I wish I could express my fears to him but he gets all upset and say if I show him what I'm feeling it will effect his trip I don't want to do that but I wish he would just comfort me and studied this a little bit more so he could reassure me that everything will be ok and all of the perminate( sorry I cant spell) effects wont take effect I hope he just does it once in a while like he says I know he wont be addicted but he is going to do the ayhuaska sorry I cant speel it, and I hope he wont get the long term effects. I don't want him to lose his memory or have violent outburst. That's all I love him very much and I don't want him to die from any drug I had so many deaths in my family and if he does I don't know what will I do. Thanks for listing guys I just needed to write how I'm feeling because I feeling some vibes that he needs to be more at peace with him self and more open and not so angry with the world before he tales it for the reason he is taking it for. I feel much better now getting this off my chest and sorry for the spelling

Peace, love, smile, happiness....

Serendip Visitor's picture

Don't be afraid, but be careful

You're boyfriend will be fine. The most recent research states that psychedelic drugs basically do more good than harm. http://jop.sagepub.com/content/26/7/994 I'd also probably let him be on his own for the most part or just around other people on psychedelics. My understanding is that sober girlfriends don't necessarily help with the safety of a psychedelic trip. Maybe let him learn about his own mind on his own. It'll truthfully probably be best.

psychonaut's picture

Baby-sitters

While it can be harmful to have an overly anxious girlfriend making you nervous throughout your entire trip (speaking from personal experience) as it can make your boyfriend more focused on keeping your anxiety down than his own, I want to say that it is almost NEVER ever ever a good idea to leave people on psychedelics unattended or amongst themselves. It is very possible that during a trip you may completely lose sense of what kind of things are okay and what aren't, and it's absolutely critical to have someone you trust with you to help make those differentiations. Especially for someone inexperienced with psychedelics. As for long-term side effects, I've never met anyone whose had "violent outburst" caused by previous trips, and unless you have a flashback to a particularly terrible trip they don't tend to be nearly as intimidating as they sound. Flashbacks generally last a couple of minutes and are basically like a very very very very weak trip, so if he's able to handle a full on psychedelic experience a flashback to that should feel more like a refreshing free mini-trip than a cause for alarm. I just want to emphasize again the importance of having a sober sitter that's sincerely accepting and preferably exited about what the person who will be tripping is about to do. Any anxieties or fears that a sober person has while babysitting someone on psychedelics will be felt and multiplied by the person tripping. As a sitter your job is to comfort, NEVER to be comforted. Remember that your boyfriend will be in a state of emotional and mental vulnerability and it is never pleasant to have to muster up the strength to comfort someone you care about while in this state. I've had to spend one of my most intense trips convincing my girlfriend and best friend that i'd be okay and I still remember this as being one of the most exhausting and debilitating experiences of my life. On the other hand I've been in situations where I was babysitting an individual who was having an absolutely terrible trip (she was someone with a lot of problems before hand and having all these things surface right in her face although unpleasant ended up being incredibly rewarding and life changing afterwords) and through simply telling her she'd make it through this and maintaining a sincerely positive approach she was able to eventually get better and now sees the experience as a good thing. The important thing is that while someone is tripping, always associate the trip with positivity, love, and acceptance. NEVER make someone feel like you're disappointed or bothered by the fact that they're experiencing the world differently than you are.

highguy's picture

You just need a release

If you are working all the time and feel stressed out? LSD can help with that. I am a full time student and on a waiter so whenever I have extra cash flow I dose the fuck out ( take acid). It changes a lot of things but not who you are as a person. don't act like your world is coming to an end just relax escape from your surroundings we will see you in a few hours. Just take it for whatever you can from the trip don't be a pussy and have some fucking fun. Blast space cadets enjoy ride see you on the other side. Peace out girl scout.
Yours truly
Lucy

Serendip Visitor's picture

read my post

Submitted by Serendip Visitor (guest) on Mon, 03/11/2013 - 11:07pm.

Amen, I became a follower of Christ after years of drug abuse.
I used LSD Many times but TRULY regret it now. I honestly believe it has affected the way I think in such a profound way.
I think about things in such great detail and depth. Which sounds great but my mind does not rest. I think and think and think about things that don't really matter. I see things in ways that many people do not, and it is a burden to be a part of society at times with people who have not altered their minds in the ways I chose to.
I suggest if you're thinking of doing acid, be aware there are consequences that will affect the rest of your life. Be wise and move forward with your life. there is life without drugs, without hate. There is hope and goodness and beauty without the escape.
Where the trip takes you. God can give you an even greater experience. I've done every drug in the book just about and there is NOTHING greater than the name of JESUS

MARYJANE's picture

LSD

Drugs are not bad - the way people abuse them is. Experiencing with your own conscience is a beautiful effect of drugs. The world we live in is so preoccupied with time and money. In reality, one cannot be defined by age or money. Rather than judging someone by looks (age) or the size of their house (money), we should judge one by who they are on the inside. Personality is the key to life. If you are negative, bad things will happen. Positive people release energy that will eventually be the result of the good things that happen in their life. The world must realize drugs are not only for people who are unhappy and need to escape reality. Happy people can escape reality to discover how positive energy changes the world. Moderation is key and knowing when it is acceptable to use drugs is what separates people from drug addicts. To me, drugs are a way of emancipation from mental slavery, a break from this world that never sleeps, and most importantly a reminder that the only thing that matters is life itself.

I do not abuse drugs. I smoke marijuana. Let me rephrase that...I smoke A LOT of marijuana. Although I do not believe marijuana is a drug, most people do. If everyone ended their day with a blunt, they would be a lot more relaxed. I have tried numerous drugs in the past - cocaine, MDMA, xanax, percocets, vicodin...you name it I've probably tried it.

LSD is the reason I do not abuse drugs. After taking LSD, I realized these other drugs I have tried were just part of my story and a new page has began. I feel absolutely no need to do any of those drugs again. I do not feel a need to do LSD again, but out of any drug I've ever tried, LSD was the most awakening experience of them all. My perception on the way the world works changed, and I believe that we are all one. No one animal/person/plant is greater than another because we are all a form of life who needs another form of life to survive.

So just remember if you decide to try LSD...do not fear a bad trip. The first and only time I did it, my driver got pulled over and the officer had no idea. I was not worried about him knowing because I was so preoccupied with the flashing cop car lights. I knew everything would work out and be okay. The officer let us go without any charges. At that moment, I realized that life works similarly to an acid trip. Everything will be okay in the end. Life has a way of working itself out to the point where everything we do will affect our lives in one way or another 50 years from now. Experimentation is a beautiful thing, and staying positive is the key to a good trip.

Lucy was wonderful in the sense that she made me aware of how beautiful this world is. I'm sure that someday I'll feel the need to take a vacation again, but what good would a vacation be if it didn't escape you from stress. By saying that all I mean is that until the day I feel stressed and need an escape I'll stick to my girl Mary. She seems to get the job done just fine.

Michael's picture

That is so very well written,

That is so very well written, thank you! You have such a good point and I can't agree more. I hope people start to realise the positive effects of psychedelics and not judge them too quickly because of the taboo that drugs have. I'm 16 and despite the fact that I've been so terrified in my bad trips, I've also learned a life lesson. I used to be a really mean person, but after I saw the horrors in these parallel dimensions or the DMT world, I began to love everything. Appreciate life for what it is, and be thankful for the things god has given me. I'm not complaining anymore over small things anymore. Psychedelics is truly a method to reveal the true world we live in. It increases your awareness so profoundly, that it will be life changing. This is not a drug and it's certainly not fun either, in my opinion. It can be fun, but it's not meant to be used as party drugs. The main purpose of psychedelics, is to be teached about certain things, see life from other angles, get a bigger view of what 'life' really is. Get a greater awareness of what the 'I' is and get to know yourself better. My first trip was a bad trip. I made an overdose of psilocybin with tons of lemon. A lemon TEK, I believe it's called. I locked my door in my room, and covered the curtains, so it was COMPLETELY DARK. After that, I've never been the same as I was before. I'm a much better person, now that I finally saw the meaning of everything. And no I'm not delusional, what you see on a mushroom trip is not an illusion. It's a tool to see the true reality. But I won't get deeper into that, due to the fact that the experiences are quite subjective, EVEN though there's many familiar experiences on ayahuasca and salvia, the two most powerful hallucinogens. Much love, Michael <3

Tom Kelly's picture

Totall agree with this

This totally explains why I (in the past, in my younger days) would feel a seretonin (almost ecstacy like) rush when getting high on mushrooms. Very interesting article and definitely sheds some light on the matter.

I have to say though, be careful with drugs you guys. As someone who experimented quite a bit in my youth, remember that the key to a good life is a sober and clear mind. Drugs are a great way to expand your mind and broaden your vision but they must be taken very carefully and should not be taken for granted, or great harm can come.

Wishing you all the best in health, life, and safety.

Sincerely,
Tom from

MysteriousSlender's picture

My remarkable childhood

Hello all,

My names Slender and im here to tell you about the magical land of milk and mushrooms. :D
Okay whatever.
On the real, Im 18 years old, my last trip was exactly 17 months ago. I've come far from my rebellious
childhood, I've learned alot. Most people wouldn't even begin to understand my experience. I did my first mushroom when
I was 14 years old. I had never smoked weed, Never smoked a cigerette either. I'd never even heard of LSD before. I was
a confused adolescent who just wanted an escape from my daunting parents. That would cut me off at ever turn I made to
tell me I was inadequate and crazy. Cause mom had any room to talk. Women thought horses were eating out her garden at 2 in the morning, while she was standing in it. Crazy bat. Anyways, I learned that day, I was gay. No it wasnt the mushrooms, I had suspected it for a long while but I was 14. 4 years ago homophobia was a big fab and everyone who valued their life would NEVER be gay. Well, Starting that day, I realized that my existance here isnt because I have to follow all my parents walks and be what they want me to be. I need to be myself, I opened up like a safe and my personality shot out like a rainbow. My parents held me back, My moms an alcoholic, and my dads addicted to Methephetamens(How the fuck ever you spell it) METH. So I was alone in the world. Well the next 2 years of my life, I was the farthest from alone, I had over 20 best friends when before I only had 1. That seemed like a myrical too good to be true. But, unfortunatly, every dog has his day. I started doing mushrooms again, ALOT. I had only done them one time, Hell what can a few more do? I was completely dead fucking wrong. My world came tumbleing down, I had anxiety like noones business, I had depression, seizures, dumb thinking, You name the side effect, I absorbed it like a sponge. I dropped out at the beginning of my junior year, 16 and i was a drop out, working at mcdonalds, living with my cousin and 4 other teenagers that took drugs like skittles. And I was the only one with a job, Theres the dumb thinking I was talking about. I deserved the "Most likely to become an EMU" award. Well after being kicked out my dads house 3 times, I finally quit it all. I felt so withdrawed from reality. Nothing was how it used to be. It was like I had jumped into a time warp that blasted me 20 years in the future and everything I had known didn't exist. Depression at its worse. Well, Like I said, I am now 18, 17 months sober, Seizures stopped, on the lowest dose of anxiety pills, living with dad, waiting for Pharmacy Tech courses to open at the local community College. Basic moral here folks, Don't do them, Unless your not gonna do them again. Every now and then is fine, Moderation is key. Consumption is chaos. Thanks for reading! (:

Serendip Visitor's picture

A-BOMB: "An Easy Trip?"

We thought that we all could flirt w/ this, "No problem", and it got really ugly. Do you see? It mastered us all. Were only better. A very special thank you to Jesus now. From Jacksonville, FL.

Serendip Visitor's picture

I've read all the comments

I've read all the comments below cause i also have some sort of side effect lately so i goole it and end up here,
Anyway,here's my story.
I'm 22 years old,done drug last year,LSD(2 time),2ci(3 times),weed(10+maybe),I'm not a drug type person,just want to try,and in my last 2ci bad try I almost kill myself,then I decided quit all the drug and seeking spiritual way.
After Vipassana,I eventually found what I want in Tibetan Buddhism step by step.

Now I'm a buddhist,vegetarian,quit smoking/drinking almost 1 year,and my mind is more clear.
But still,i will never forget every trip I ever had,and whatever the past is,I felt greatful for those life changing experiences,but now I don't need drug anymore.

Sometimes I still have those psychedelic feeling when totally drug clean,but I know I'm getting better,day by day.
Buddha can give you all the answers in the world,including what drug offers you.
We don't need drug,we need religion.

benfromgr's picture

i have been reading many of

i have been reading many of these comments and there is one trend that remains consistant throughout the posts, religion. so many of you say you were atheist or a nonbeliever until you found God but you never stop to remember what helped you find god. the same thing you condemn helped many of you find your religious calling. And drugs are terrible when they are abused there is no doubt about that but you have to realize that you also can become so much more aware on these drugs. If you truly want a religious experience go out to the forest to camp with a bonfire and guitar and drop shrooms. life changing experience. You learn so much about yourself and what you want from life by doing that. But to just blatantly accuse all drugs to be evil without the chance is ridiculous and absurd. You might as well go after caffeine and sugar since they are turning my generation into a bunch of lazy computer-centralized culture. I was 210 pounds at 15 when i was at a massive bonfire and tried LSD which changed my life. Made me realize that I needed to lose weight for my health and also helped me understand what i want, professionally and romantically as well as my friendships. Yes I cut people off who were headed for a bad direction but you can not place all drugs into one box and call it good. Finally at the age of 17 I am 137 pounds and in the greatest shape since I was 11, running every day while also being able to enjoy marijuana, having a job, a car, 3.1 gpa. Maybe I'm just a exception but I like to think that it's because of that magical night I had a couple of years ago

Serendip Visitor's picture

pizza

i like pizza for breakfast lunch and dinner!!!

Eric M. Wiggin's picture

FROM A MAFIA WIDOW...

Ring-ring!! It’s my friend Mr. Ed Colton, and he has a book which he and a close friend of theirs (MR and Mrs. Colton) wrote. Their book is titled: “From a Mafia Widow to God’s Child”. I’ve got to go; we’ll talk in a little while If I may have just a moment to speak with you all. If you like to roll up a joint, you can’t go one day without smoking marijuana because you keep on jonesing for it; you’re a youth, what I’ve just described, you maybe fit in the picture, or maybe you’re an adolescent and you’re not quite yet 18, and you run with the wildest bunch in the town, get the book. I want you to get the book.

Sukie DeMarko's picture

Pfft....

Pretty much just making this post, to point out...that God cannot help you with your drug addiction. Only YOU can help yourself. If you, or a loved one have used and/or using the drug currently....start going to special meetings to halt this addiction. I mean, it isn't like there is no one out there to help you. First things first, talk to your kids/friends/neighbors about the harsh realities of drugs...it could/will prevent more drug users in the future. I am only 17, but I have been offered weed and other substances since I was 10. I have never picked up a cigarette or a needle, and I am in almost perfect help. My only addiction, is to the drink Sunny D. I've got family and friends who do drugs, and I try my best to talk them out of doing such things. They all go to church and whatnot, like that helps -.- I do not go to church, I do not need "God" to keep me on the straight and narrow, on a path of purity through life...or whatever it is that people say. Just do not start the drug in the first place...and if you have been on the drug...see someone about it. And never start a drug due to life problems, there are better means of getting over your problems without the use of a deadly substance. I've seen far too many suffer from the effects of drugs, and I do not want to have to hear about someone else's death because they tripped out on LSD or something of that sort, and killed themselves.

Eric Wiggin's picture

I've tried Lysergic Acid Diethylamide

With no special regard to the "out of body" phenomenon: I still do not like where it took me. "In the body, out of the body, and then in the body again", I still am in no possition to assert that all. Whoever coined the term/expression mind -expanding was a little looney. Were'nt they? If a person is going to pass away wouldn't it be better for that individual to pass on without having an illicit drug problem?

Eric Wiggin's picture

Believe in Devils (?)...

I'm speaking to some of you. If you repent now, and go to work for someone (just keep in touch with a few law abiding citizens) you will help us all to slow & to stop this devastating habit or destructive trend.(consider it) Fewer people serving prison time. Hallucinogens can cause unpredictable behavior. Some of you are going to die if you keep on, because Law Enforcement has to use force on the dangerous individual posing a threat. Some, in times past, have resisted arrest and others have assaulted a Law Enforcement Officer. It has risks and it will be to your own expense !

Eric M. Wiggin's picture

Mind Altering Drugs

Don't do it. Really, it's a lot of trouble that you cant afford.

Eric Wiggin, A.A. Criminal Justice's picture

LIBRARY/THE END...CHOMPCHOMPCHOMP

I turned to drugs for everything. I believed it was the solution...It was before 11 P.M.. It was 1993, I was staying over Mr. Bodenshatz house for the night. I was feeling excessively hot one moment then cold the next. I started having tremors in both legs. The sense of calm left and what I had would next begin to experience would defy reason a little bit; fear, fear an immense fear without provocation (sum of every fear, of diverse fears that most would experience over a lifetime). This is where I seem to draw a blank untill I rose up to go walking. I believe that outer darkness was holding me. There was indeed some hallucinating (when I felt a little normal again). I walked the North Side with someone. One other reason for my belief (i.e. it's a Locale 1, an O.B.E.) ? Ans: The weighty burden that's so hard to shed !

Do anything like that again ? I never will, I settled it at about 11 P.M. on the N. Side, at the Bodenshatz home-- never again !

Eric M. Wiggin's picture

Think that you can't change ?

Yes, I'll be certain to speak of God. I sure as heck don't fear simply a man who may destroy me in this life, and may never destroy my soul. Friend, the key to eternal security is Jesus Christ. His word-- the bread of life. Don't partake unworthily. Be a hearer and a doer. I can never say that some one abusing a substance is right. It's so wrong.

Serendip Visitor's picture

Amen, I became a follower of

Amen, I became a follower of Christ after years of drug abuse.
I used LSD Many times but TRULY regret it now. I honestly believe it has affected the way I think in such a profound way.
I think about things in such great detail and depth. Which sounds great but my mind does not rest. I think and think and think about things that don't really matter. I see things in ways that many people do not, and it is a burden to be a part of society at times with people who have not altered their minds in the ways I chose to.
I suggest if you're thinking of doing acid, be aware there are consequences that will affect the rest of your life. Be wise and move forward with your life. there is life without drugs, without hate. There is hope and goodness and beauty without the escape.
Where the trip takes you. God can give you an even greater experience. I've done every drug in the book just about and there is NOTHING greater than the name of JESUS

Serendip Visitor's picture

effects of lsd

This guy shared in his testimony that he did alot of drugs and then got saved in teen challenge. I really believe he is still suffering the effects of his drug use and was not truly healed of the damage it has done, yet he has truth, but you can truly still see the effects:
http://youtu.be/duIMjTDbC0M

Serendip Visitor's picture

Follower of Christ

Love your post and agree with you 100%. Whether people believe it or not it is a fact that we can do all thing through Christ Jesus. I know I been there and am so blessed to had come back to Him.

Happy Addict's picture

Temporary Psychosis

I took LSD and Psilocybin mushrooms on a regular basis in college for 2 years. My belief at the time was this would augment the use of marijuana and alcohol to escape emotional pain, self-medicate, and search for a deeper self-understanding. It was difficult to translate the drug induced experience to the few times I was not high.....although I do feel that these drugs helped my academic performance by masking my deep sense of self-loathing and depression.

After a time, I felt that the way to move forward with inner exploration was to take larger doses of hallucinogenics in the hopes of achieving a temporary psychosis. It was my belief, that experiencing a form of temporary insanity would lead me to greater truths about myself and the world. So on four separate occasions I took 7 hits of acid, 10 hits of acid, 15 hits of acid, and then an ounce of psilocybin mushrooms (made me vomit). These were intensely uncomfortable experiences and whatever insights, images, or meaning was derived, I was unable to translate to a non-drug experience at that time in my life.

I am now 53 years old and 24 years sober. With nostalgia, I fondly look back on these earlier attempts to search for meaning and spirituality. If not for the drive to examination myself, I would not be sober or alive today.

Worried Newbie's picture

Addiction

I have similar issues to what you used to have and I recently have started using acid I find with every use I have benefited, the only thing is I'm worried if I continue the use of it I'll become dependent on it and my life with go in the gutter. How do you know if you're using it casually to crossing the line to severe addiction. Everyone I'm around assures me it's find and that it won't harm me nor will I get addicted but they're all frequent users so I'm not sure whether to trust their judgement or not thus I am seeking a second opinion.

Brynn's picture

LSD and addiction

From my research, I found that LSD is not attictive in itself. It is possible to become 'psychologically addicted' to any drug, however. No withdrawls or anything like that with LSD, however. The 'bad' possible side effects are suprisingly few, considering all the hype about LSD. I am a former user, more than 15 years clean. I was never addicted to it in any sense, and i do have whats called 'an addictive' personality. I can't condone drug use, but if someone were to try some LSD i would suggest doing it at home, with several trusted (and sober) friends to watch out for you. The effects begin up to an our after ingestion, and end within 8-12 hours, depending on the dosage. A good nights sleep AFTER the effects have worn off is the best thing for it. Like I said, make sure you have good, trustworthy friends around you, to calm you down if need be. Using this drug in the home, or somewhere familiar and comfortable would be advisable. Take into account your state of mind BEFORE using LSD. If you're generally happy you will most likely have a 'good trip'. If, howver, you are angry, upset, etc, you will most likely experience what is know as a 'bad trip'.

I hope that this has helped, even a little. There is so much information out there about the good and bad of lSD, please do some research first before using. At least to know somewhat to expect. Again, I hope my lil rant has been helpful.

Do take care, and I would be interested in hearing how things go for you.

Brynn

Happy Addict's picture

I don't know how your use of

I don't know how your use of acid effects you. The fact you have concerns about the possibility of addiction means something. There is no easy way of determining if you are being harmed, unless there is a noticeable short term change that you link to drug use. It is more difficult to site a baseline that you can use to monitor long term effects. The line between casual use and addiction is not well defined (blurred) and although each individual experiences the demarcation between the two differently.....there are some commonalities to look for. For example, if you begin to define how you see the world from the perspective of the drug experience, then your identity (and the wiring of your brain) begins to shift in that direction.

As humans, our brains are all wired to seek pleasure...that is how we survived (eat, have sex, etc)....drug experiences (among many other things offered up by modern society) give different meaning to what constitutes pleasure. Unfortunately for us, the results of this experiment are not in....so we don't have hindsight or wisdom to help guide us. So to some extent we are all lab rats in this great experiment in neuro-plasticity (re-wiring of the brain).

So when you speak of your experience of benefiting with every use...it sounds like a gift. One concern I have is how can any human have an accurate perspective on the effects of how their thinking and being interacts with technology, because consciousness and thinking in humans evolved at a time when survival and reproduction were the driving determinants of genetic selection. We have the wonders of modern technology, with the nervous system and emotions of stone age humans.

neuropsych's picture

Psychedelics like LCD,

Psychedelics like LCD, hallucinogenic mushrooms, mescalin, DMT ect. are not physically addicting drugs. Yes they can have mentally addicting qualities but that is dependent on the user. These drugs (not including narcotics, alcohol, tobacco or any other street drug) can be very beneficial if used correctly. I "trip", using LSD most frequently, approximately once every two to three weeks. Although I would like to use them more frequently I don't because I feel that drugs need to be respected and done safely in order to find the benefits. I also have suffered from sever depression and anxiety and know how debilitating it can be. Using psychedelics has been very beneficial on my road to recovery and self-exploration. Aldous Huxley says it better than I ever could in his book Heaven and Hell. As a neuropsychology major I hope to study in more depth the psychological effects of psychedelics because little to no research has been done on them. I hope one day they will not be looked at as a "drug" but a way to aid in the expansion and exploration of the mind.

Serendip Visitor's picture

I have 17 year old who is

I have 17 year old who is struggling now with the effects of this drug and he is an entirely different person from a few months ago, I am working to get him into rehab. How were you able to kick it?

Happy Addict's picture

re: 17 year old who is

I appreciate the courage it took to share your experience. I have children who are close to that age, so I can only imagine how disruptive and painful your situation could be. When I went to rehab at age 29, I quite literally was faced with the choice of quit or die. Although I felt a sense of defeat that I didn't drug/drink myself to death, there was also an unburdening of feeling trapped in an existence that felt horribly and painfully out of control. I was in so much pain, I was ready to try something different. It took time, life experience, suicide attempts, and a previous failed rehab for me to become ready.

As for your child getting into rehab.....age 17 is a very different place to be in life, than when I went to rehab. What I mean is that it is difficult to get and stay sober when it is your choice.....and more difficult under other circumstances. On the other hand, if you act quickly while he/she is still a minor they may be some legal remedies. You may be able to make decisions for your child, without the child's consent or agreement, as long as the child is a minor. If the personality changes have made him/her difficult to reach, a professionally structured intervention may provide an opportunity to expose your child to a different perspective on drug use. Are there any resources in your community, your schools, or professionals that could help you?

I don't know your child. At age 17. drug use certainly makes sense as a response to past trauma, current pain, and useful as a strategy for non-compliance with authority, relationships, societal norms or expectations.

For some people drug use is an existential solution to living in a world they believe to be not of their creation, where the inevitable collision between advanced human technology and stone age human emotions leaves people dislodged from any sense of being grounded in a safe or meaningful existence.

Samantha's picture

Effected by shrooms

I'm 18 years old and did shrooms back in july it is now September and i still feel the effects of "tripping" and seeing things and looking at things and they start moving. I just want it to stop and to never do them again! does anyone know a solution? detox of the body? anything?

Serendip Visitor's picture

Not true

I don't buy it. You are over-exaggerating the effects of this drug and are quite simply spreading misinformation. Even if you did develop HPPD (which has not been confirmed to exist), those are not the symptoms of it and it is normally after massive amounts have been ingested for long periods of time.

I must say though that I do sometimes see certain things that REMIND me of tripping, but I am most certainly not tripping.

So, there are two possibilities:

A: You are lying/observing a placebo.
B: The psychedelics have speed up the development of schizophrenia or a similar disorder that was already on its way... which again, almost always takes more than one trip.

These kind of statements appall me.

Avid drug user's picture

Effected by shrooms

I am so sorry.... at least its not a bad trip right? just a really annoying one.. you' re stuck for life... sorry again

Eric Wiggin's picture

Why I am drug-free now

Now? Now-a-days I have a reason to remain drugfree , because I don't feel short changed in this life. My mother? My mom is not a bad mom. My father? How would you like to be told that I dialed 9-1-1, then police came out with thier guns and got very real with him. Dad never struck me again after that.

Serendip VisitorEric M. Wiggin's picture

LSD BERRIES GROWING ON A TREE ?!!!

People treat me like dirt because they don't understand deliverance. They can only stuggle, and they struggle very hard with the potential effect of Canabis and LSD. They try to apply science to me, when I have been entirely delivered, and live for the Lord now. I have an attitude? YES I DO. The authorities see the offense, and do not often seek God's help to see the true nature and true mottiffs of their own, in regards to myself. The only thing I know about is little more than 60 hits in the span of time covering some of 1991 and most of 1992. For more than three months six to eight of us, or a few more, went through them all. Not everyday users. No one was exposed to massive quantities.Drug experimenters, and a juvenille offender (me) even, but no everyday user ever around. I was charged once when I had canibas. Not all of the authorities are so ignorant some have recieved a new heart from Christ, (Christ, Jesus) after hearing the Gospel. I can have confidence in them. IT"S THE REST !!!

Serendip VisitorEric M. Wiggin's picture

Mission Heavenward

I've once heard the testimony of someone that had a Locale 1 vision, an out of body experience and went to Hell, all while messing with LSD. I've asked myself from time to time if I've had one too, but I am more firmly convinced that it was merely a bad trip. I experienced panic, and I had thoughts and perceptions, and so forth, that left me really terrified at that time. I had the fear that I was never going to return to my right mind ever again. I never went bak to the stuff. I've placed my faith in Jesus Christ since. Am I plain crazy? Am I born again?

Serendip Visitor's picture

Thinks this.

In my opinion if you want a real true experience of spirituality like Jesus and Lord Buddha and other great than Meditation is the one of the best ways. But drugs is not the way.

Thanks,
SB

shari's picture

Jesus

Jesus is THE answer. He has it all! Not drugs, sex, etc.!

CooKiEz's picture

Jesus....

So if Jesus has it all, why doesn't he have drugs? I'm sure Jesus wouldn't mind sesh every now and again.

Serendip Visitor's picture

reply

You seem to have done enough drugs to have lost the ability to spell and form sentences

Serendip Visitor's picture

Wow....

You seem to have become very preachy and judgmental of others for someone who is a "Christian". Also, I have done shrooms a few times, not LSD yet, and I had an amaZing time.......

Serendip Visitor's picture

There is positive alternative and may be more powerful than this

Its very easy, but yet only true people understand. Its legal, positive, beneficial and takes you there which is real. True Real. It takes you to spirituality. ( Every true person, who try for spirituality, ( in my opinion) they will get)

One of the ways is (Proper) Meditation. (This is what I am talking about. This is the easiest
way)
Everything is possible. Any person can leave any habit(s), if he wants. One of the ways is Meditation. And of course spirituality is great.

Check by your self.

Thanks,
SB.

Matthew's picture

Moderation

Everything comes with a price, some of the consequences of taking drugs for long periods of time can be very bad in the long run. I've done my share of heavy drugs, in fact i was pretty much do or die dont give a hell type of person at the time and got myself into alot of things i should have never went anywhere near. But i do have to say the hallucineogenic's iv done (Lsd-xtc-shrooms-dxm-) Benadryl in large doses makes you loose you mind for just as long as an acid trip. When you want to use drugs to get high like i did things tend to get out of control. Control and moderation combined with certain drugs can have positive effects on your life. They can cure illnesses that are rare and hard to cure. They can help one become their true self, It opens you up to a world of love and appreciation. Mankind has free will and self indulging in something so powerful based upon greed was not the purpose of these drugs. Instead of being greedy and taking more than you should because your not high enough realize the potential your mind has and use it to learn. Knowledge is king and without it you could not survive. But if you could learn infinite knowledge you could very much live forever. Although that seems like a far fetched idea in todays day and age it really does not, People are not open enough and i believe Lsd or mushrooms may have some of the best eye opening effects known to man. Controlling your trip is important, dont get lost in useless thoughts, there are things out there worth discovering and there are things ment to be left alone. Fear and negativity is a huge factor in a "bad trip" if you let go of fear and realized your minds potential to keep you save you would have nothing to fear. Don't do too much. Dont do it if your under age as your mind and body has not yet matured and the trama's can be life threatening. When you dont understand something you cant control it. Research is key, do not do anything without checking its backgrounds from multiple sources. Realize with information you can prevent a "bad trip" Know your surroundings. Be familiar with the environment you are in. If the environment presents any negativity do not trip there. Positive friends can be an essential role in a perfect trip. Especially having a friend to trip with and a friend to help keep you physically and mentally safe. IF anybody needs any advice or information i have a damn computer shoved inside my brain lol, i believe lsd and trippy drugs made me able to learn at a faster than normal rate. I read about physics and listen to videos about spirituality and every single aspect that comes with it, including ancient theories and covered up truths.

Serendip Visitor's picture

Still Trippin?

Hi,

A friend's son has been acting as if he is tripping for about a year and a half. As time has gone on it's gotten worse but he does have moments that he comes out of it. I've been around many people while they were tripping and this is exactly how he acts. We are concerned that he will be treated with drugs that won't help him and or potentially cause more damage.

Serendip Visitor's picture

Answer to still trip pin

Hi, my daughter took acid a few times and then almost a year ago a drug called 2ce. She hasn't been the same since: changed perceptions, occasional hallucinations, anxiety, depression, feelings of darkness. We've been reluctant to try medication as we feel like she is, in a way, recovering from a "brain injury" and want to give her brain the chance to return to normal functioning. She lost her job, most of her friends and is unable to function on a completely normal level.

Anyone who messes with their brain chemistry is playing with fire. To attain enlightenment, go the hard route of meditation and practice.

Lynn Mayer's picture

Help me

My son said he started acid/pot together when he was 11. Now he is 18 and in jail. I need advice.
Desperate mom

jay-cub's picture

word from the wise

im currently 17 and i started weed when i was about 9 or 10 and i starded acid/L.S.D lot too much later im not quite sure what kind of advice your seeking but i can asure you that it was not the weed that possibly ended him in incarceration but more likey the acid when your under the effects of a mind altering suject such as acid your surroundings and community play the biggest roles in ones trip for instants a rave (techno/dubstep laser/light show)can appear anywhere from seeing hells pit become reality to heaven on earth and i mean that litterly so deppending on where he was is what could have happend...however if your seeking to helphim your best bet would be to while giving him space gently let him know what he means to you occaisionily let him know your becomeing worried about his habbits show that your worried though not like your trying to force him to top or change his life because doing so will only make him want to do that much more to prove he runs his own life.....it could possibly be a alongated experimental phase do to exposure at an early age by no means am i anywhere near a psychologist but i have been studing psychology for about 6 yeara now and it seems like hes not turning into a criminal by any means he's simply trying to expierience all asspects of life i hope that my knowlage has been of some insight for you and i hope you and your son will retain a strong relationship such as my mother an i have.

Matthew's picture

The first time i started was

The first time i started was when i was 14. I started with weed and went straight to lsd and binged on that for a while. It takes a strong mind to make the decision to fix your problems yourself and realize that only he can change his life. I spent just 4 months in jail and when i got out i got into blow really bad and everything else. I ended up spending 2 months in a rehab and with a strong mind i stopped everything but cigs. Just support him and give him as much advice as you can. Explain that drugs are not ment to be abused no matter weather its illegal or legal over the counter stuff. Too much of anything can mess you up. Giving your body a break and learning about drugs is my substitute. In the last 6 years i have done lsd 3 or 4 times but only a couple of tabs. Rather than go crazy and take 7 or more like i used to i learned the value of moderation. Tell him to focus and its easy as hell to get back in the right track.

Serendip Visitor's picture

so people who stop taking it

so people who stop taking it how long will it take them to return back to their regular state of mind

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