The Effects of Hallucinogenic Drugs on The Brain
1998 First Web Reports
On Serendip
The Effects of Hallucinogenic Drugs on The Brain
Alicia Ebbitt
Hallucinnogenic Drugs alter a person's perceptions of reality and may cause hallucinations and other alterations of the senses. Drugs classified as hallucinogens include: LSD (lysergic acid diethylamide), 2,5-dimethoxy-4-methylamphetime(DOM), N,N-dimethyltrptamine(DMT), psilocin, and mescaline. There are two aspects of these drugs that classify then as hallucinogens. They all have common side effects, including distortion of sensory perception, and other psychic and somatic effects. These drugs also exhibit cross-tolerance. This means that a user of hallucinogenic drugs develops a higher tolerance to hallucinogens, the more they are used and the shorter the time span is between the last usage.Hallucinogenic drugs have been used throughout history for a number of reasons. They have been used as medicinal agents as well as having served religious purposes. Hallucinogens such as mescaline have been used in Native American ritual ceremonies. There was extensive usage of hallucinogens in the 60's and 70's as part of the counter- culture hippie movement. During the "acid tests" of this era, hallucinogenic drugs were used for mind exploration (B.L. Jacobs, "How Hallucinogenic Drugs Work").
Hallucinogenic drugs cause both physical and psychological effects on humans. The physical effects of these drugs include: dilated pupils, elevated body temperature, increased heart rate and blood pressure, appetite loss, sleeplessness, tremors, headaches, nausea, sweating, heart palpitations, blurring of vision, memory loss, trembling, and itching. A user of hallucinogenic drugs will also experience a number of psychological alterations in the brain. These drugs may cause hallucinations and illusions as well, as the amplification of sense, and the alterations of thinking and self-awareness. It is quite possible to have a bad reaction to hallucinogenic drugs. This is referred to as a "bad trip" and may cause panic, confusion, suspicion, anxiety, and loss of control. The long-term effects of these drugs can be quite dangerous. These long-term effects may include: flashbacks, mood swings, impaired thinking, unexpected outbursts of violence and eventually possibly depression that may lead to death or suicide.
Quite a lot of interest concerning hallucinogens has been generated by neurobiologists and other scientists. The effects that hallucinogenic drugs have on the brain are quite complicated and very interesting. Many users of hallucinogenic drugs have experienced whole personality changes which raises questions about the relationship between brain and behavior. Scientists are also curious as to how total alterations of the senses can occur as the result of hallucinogen usage. Many people that have used hallucinogens claim to have "seen sounds" or "heard colors". Scientists ask questions such as: How can a person under the influence of hallucinogenic drugs see things that aren't there? or How do flashbacks work? Another aspect of hallucinogenic drugs that interests scientists is that they are psychomimetic meaning that they mimic certain aspects of psychosis. Through the use of hallucinogenic drugs, one can induce temporary symptoms of psychosis.
As a result of the great interest in hallucinogens, many years of research have been done to try and determine exactly how the brain is affected by these drugs. Scientists have tried to determine if there is a specific site in the brain where hallucinogens act. This has been difficult to determine. Scientists still are unable to answer all questions about hallucinogenic drugs. However they have been able to determine certain areas of the brain that these drugs do act upon.
Early on in the reasearch on hallucinogens, it was determined that hallucinogenic drugs structurally resemble serotonin (5-HT) Serotonin is found in specific neurons in the brain that mediate chemical neurotransmission in the brain. Neurons containing serotonin can be found in the brain stem section of the brain. Axons of serotonergic neurons project to almost every part of the brain, affecting and communicating with all sections of the brain. Serotonin also acts at many receptor areas of neurons. Because hallucinogenic drugs are structurally similar to serotonin, it was theorized that hallucinogenic drugs may act upon serotonergic neurons (B.L. Jacobs, "How Hallucinogenic Drugs Work").
Scientists began to carefully study the serotonin system and found out that hallucinogens do in fact have some kind of effect on serotonin. Hallucinogenic drugs cause an increase in the level of brain serotonin, but they inhibit the rapid firing of neurons containing serotonin. This is a negative feedback system in which as the serotonin level rises, the activity of serotonergic neurons decreases. It was originally theorized that this effect of hallucinogenic drugs directly caused sense alteration and hallucinations. Several observations however have shown this theory not to be true. These observations include the following: Low doses of LSD effect behavior, but do not depress firing of serotonergic neurons, The behavioral effects of LSD outlast the alteration of the firing of the serotonergic neurons, Repeated dosage of LSD results in a decrease of behavioral changes, but still effects neuron firing, Other hallucinogens do not affect serotonergic neurons, When serotonin levels are depleted, the effectiveness of LSD is not eliminated (Ian Leicht, "Postulated Mechanisms of LSD").
It has now been determined that the effects of hallucinogenic drugs are actually caused by the effects that hallucinogenic drugs have on the post-synaptic activity of serotonergic neurons. Hallucinogenic drugs directly affect the serotonin receptors(specifically the serotonin receptor subtype, 5-HT2), which is what eventually results in a complex pattern of action potentials and activity. This was proven by the fact that the depletion of serotonin levels in animals does not result in a decrease of behavioral effects caused by hallucinogenic drugs (B.L. Jacobs, "How Hallucinogenic Drugs Work").
Hallucinations and other effects of hallucinogens are however very complicated experiences. They are not simply a part of a cause and effect system in the brain, where hallucinogenic drugs act on serotonin and cause hallucinations. Instead, hallucinogenic drugs act initially on the serotonin system, which sends into motion, a pattern of complex action potentials and activity. Other neurotransmitters may be involved in these activities as well. The effects that inputs and outputs have on each other in this system as well as the pattern of action potentials mediated by hallucinogenic drugs help to cause many of the complex changes that allow hallucinations to happen. (B.L. Jacobs, "How Hallucinogenic Drugs Work") Scientists continue to do research to determine the exact effects that hallucinogens have on the serotonin receptors and to answer any questions that they cannot yet answer.
WWW Sources
1) NIDA (National Institution Drug Abuse: LSD(Lysergic Acid Diethylamide).
2) Hallucinogenic Drugs in Psychiatric Research and Treatment: Perspectives and Prospects.
3) Tryptamine Hallucinogens and Consciousness.
4) Hallucinogens (PCP, LSD, etc.).
5) Narcotics, Dangerous Drugs, and Marijuana.
6) Healthguide Online: Substance Abuse: Hallucinogens.
8) Los Angeles Police Department Drug Recognition Expert Unit: Hallucinogens.
9) Postulated Mechanisms of LSD.
10) B.L. Jacobs. 1987. How Hallucinogenic Drugs Work. "American Scientist". 75:385-92.
11) M.C. Bindal, S.P. Gupta, and P. Singh. 1983. QSAR Studies on Hallucinogens. "Chemical Reviews". 83:633-49.
Comments made prior to 2007
When you list the drugs in the beginning of your article you list lsd psilocin and mescaline. But "psilocin" is not actually the active ingredient in hallucinogenic mushrooms. The correct term is "Psilocybin". Just thought I'd point that out ... Daniel, 19 February 2007



Comments
Thinks this.
In my opinion if you want a real true experience of spirituality like Jesus and Lord Buddha and other great than Meditation is the one of the best ways. But drugs is not the way.
Thanks,
SB
There is positive alternative and may be more powerful than this
Its very easy, but yet only true people understand. Its legal, positive, beneficial and takes you there which is real. True Real. It takes you to spirituality. ( Every true person, who try for spirituality, ( in my opinion) they will get)
One of the ways is (Proper) Meditation. (This is what I am talking about. This is the easiest
way)
Everything is possible. Any person can leave any habit(s), if he wants. One of the ways is Meditation. And of course spirituality is great.
Check by your self.
Thanks,
SB.
Moderation
Everything comes with a price, some of the consequences of taking drugs for long periods of time can be very bad in the long run. I've done my share of heavy drugs, in fact i was pretty much do or die dont give a hell type of person at the time and got myself into alot of things i should have never went anywhere near. But i do have to say the hallucineogenic's iv done (Lsd-xtc-shrooms-dxm-) Benadryl in large doses makes you loose you mind for just as long as an acid trip. When you want to use drugs to get high like i did things tend to get out of control. Control and moderation combined with certain drugs can have positive effects on your life. They can cure illnesses that are rare and hard to cure. They can help one become their true self, It opens you up to a world of love and appreciation. Mankind has free will and self indulging in something so powerful based upon greed was not the purpose of these drugs. Instead of being greedy and taking more than you should because your not high enough realize the potential your mind has and use it to learn. Knowledge is king and without it you could not survive. But if you could learn infinite knowledge you could very much live forever. Although that seems like a far fetched idea in todays day and age it really does not, People are not open enough and i believe Lsd or mushrooms may have some of the best eye opening effects known to man. Controlling your trip is important, dont get lost in useless thoughts, there are things out there worth discovering and there are things ment to be left alone. Fear and negativity is a huge factor in a "bad trip" if you let go of fear and realized your minds potential to keep you save you would have nothing to fear. Don't do too much. Dont do it if your under age as your mind and body has not yet matured and the trama's can be life threatening. When you dont understand something you cant control it. Research is key, do not do anything without checking its backgrounds from multiple sources. Realize with information you can prevent a "bad trip" Know your surroundings. Be familiar with the environment you are in. If the environment presents any negativity do not trip there. Positive friends can be an essential role in a perfect trip. Especially having a friend to trip with and a friend to help keep you physically and mentally safe. IF anybody needs any advice or information i have a damn computer shoved inside my brain lol, i believe lsd and trippy drugs made me able to learn at a faster than normal rate. I read about physics and listen to videos about spirituality and every single aspect that comes with it, including ancient theories and covered up truths.
Still Trippin?
Hi,
A friend's son has been acting as if he is tripping for about a year and a half. As time has gone on it's gotten worse but he does have moments that he comes out of it. I've been around many people while they were tripping and this is exactly how he acts. We are concerned that he will be treated with drugs that won't help him and or potentially cause more damage.
Help me
My son said he started acid/pot together when he was 11. Now he is 18 and in jail. I need advice.
Desperate mom
The first time i started was
The first time i started was when i was 14. I started with weed and went straight to lsd and binged on that for a while. It takes a strong mind to make the decision to fix your problems yourself and realize that only he can change his life. I spent just 4 months in jail and when i got out i got into blow really bad and everything else. I ended up spending 2 months in a rehab and with a strong mind i stopped everything but cigs. Just support him and give him as much advice as you can. Explain that drugs are not ment to be abused no matter weather its illegal or legal over the counter stuff. Too much of anything can mess you up. Giving your body a break and learning about drugs is my substitute. In the last 6 years i have done lsd 3 or 4 times but only a couple of tabs. Rather than go crazy and take 7 or more like i used to i learned the value of moderation. Tell him to focus and its easy as hell to get back in the right track.
so people who stop taking it
so people who stop taking it how long will it take them to return back to their regular state of mind
very intersting
id like to know more about the effects of doing drugs on your brain...have u ever done air duster?
the truth about hallucinogens
right, i'll get right to the truth about LSD. you have to be pretty brave to try a substance like LSD because it is a powerful and life changing/affirming experience - you will never forget it. so, to all those interested in changing the organic structure of their mind and soul potential i have this to say; the experience can often be frightening/ puzzling/ disturbing/ emotional /strange etc, and if you arent expecting such an experience then i advise you to stay well clear of any hallucinogen. however - these are experiences you will all live through in your lifetimes, and LSD will treat you to a minimum of 12 hours of the wildest and strangest dream you have ever had and you will remember it well, someday! but until you do remember, look around you and remind yourself of who you are and what experiences changed your life, because LSD will be one of them.
Do it or not to do it? PLEASE READ
Im a 22 year old woman now, i had an addiction to LSD at the age of 19, i lost my sister to cancer when i was 17 (her twin sister was still battling it) and started taking acid after that on a regular basis. by the age of 19 it had become an almost daily thing. i had left uni at the end of 2008, going back every now and then to start up again (i was doing a double major in psychology and classical guitar), but i was too fucked. i had no job, and busked as a living while still living at my mums house. LSD had become my heroin. i needed it all the time, couldn't wait to just trip and go through my daily bores with the glorious colours of the drug, see the wonderful thing no one else could see..
they say you can't physically get addicted to it, but when your only escape from the world is a beautiful drug that makes you think completely differently and see the world in so many shapes and colours, why wouldn't you want more? i mean, after all it, its not gonna kill you, so why do something like heroin or crack when you can have so much fun and see so much beauty on acid and not get physically fucked up! (unless of course you trip out and cut your arm off or something)
the only thing it can effect is your career, your family, your relationships, your memory, your life.
but hey, if you can deal with having to go to the doctor every couple of months to get your zyprexa (antipsychotic drug used for bipolar and schizophrenics) and zoloft(antidepressant) script filled so you don't trip out all the time (floors are ALWAYS moving, patterns everywhere in everything, people calling out to you, hearing things) then go for it.
And i stopped at the age of 21. its been a year of treatment and I'm still fucked
some people have adverse reactions to it, some people don't. but you gotta look at the pros and cons of taking it and see whether or not you would like to take the chance of spending the rest of your life mentally FUCKED UP, in and out of psychs all the time and basically having to rebuild your life.
I can't say i will ever regret having the experience as it was wonderful all the while being fucked up, whats done is done, BUT i can say that if i had another chance, i wouldn't touch it. i would be earning over 150 dollars every 45 minutes by the end of this year if i didn't -.-
This is what happens when
This is what happens when you're greedy for that amazing world. Yes it's so so so great, but you cannot be greedy or you'll be punished in this way, and you truly got a bad punishment. It's disrespectful to it. You have to humble to this drug. Just use it to learn and know about you, and your world, and then you let it resonate within in you for a long amount of using what you've learned in this world that you've been put in to. Don't try to stay out of this one and in to another that's not where you're supposed to be, and you'll never truly be there you'll only fuck the things up in the world that you are. Just learn from that world, and take what you've learned with you in to this one. If you disrespect it; it will disrespect you back I'm sorry to say.
bad trips are one thing
bad trips are one thing nearly losing your mind makes u happy for every moment of life but i say acid is as bad as as alot of other class a drugs depends on the enviroment if u start having a bad trip or dont like the people then leave the area
i did it more times than i
i did it more times than i should of iv experienced hell nd heaven on it nearly lost my mind from it went through 20 hours of hell nd to tell u the truth its not worth it nd if u need to see it ur self then u can i have take 3.5 tabs taken tabs for 5 days straight could handle it but if u do it to much it damages your mind nd will leave u fuked like i am atm im 18 nd toke it probaly aropund 40 times when i was 17 if u do it do it twice or 3 times a year nothing wrong with doing it just dont do it 2 much nd prepare for it by working out doing martia arts nd meditating
Ignorance.
I have done Acid. and i can honestly say this it has changed my life for the better' i use to be so shy and acid opened my eyes to the reality which i believe everyone should experince. It has a spirtial effect and a person impact. But again this all depends on wether the person taking acid is ready: not just physical but mentaly. I had the most amazing experince of my life. Its like a world i have never seen before. you have to take chances in life to live' some you regret some you don't and i sure as hell dont regret acid. It was one of the best choices i have made. Acid didnt change the way i learn or iformantion that i have known. it did change how ever my point of veiw on life, in a complete good way. Just like Albert Hoffman the creater and founder of LSD said;
"I think that in human evolution it has never been as necessary to have this substance LSD. It is just a tool to turn us into what we are supposed to be." You can not judge the effects of lsd ifyou have never incountered or experinced it yourself. you cant say that it destroys your brain' when ive done it more than once and my brain is healthy as ever. doctors found nothing in medical reports to be wrong with me when i went for my Cat scans. Lsd i belive is a life changing experince.
LSD Ravished 17 years of my Life
Hallucinogenic drugs for one person are always a completely different life experience than for another person. The most important consideration when using a hallucinogen or any drug for that matter is your genetic propensity toward mental illness or brain chemical imbalances. The biggest regret I have is getting lured into using LSD and the Blaze at around 13 years of age. I didn't know what my family history for mental problems was at that time. Because I used LSD at 13, my life up until today (I'm age 30) has been a constant struggle and roller coaster ride in both my social and professional lives.
I now know that my mother's aunt had schizophrenia, my father suffered with depression/anxiety and some sort a sleep or attention disorder, and my mother has suffered with depression/anxiety and what seems to be an attention disorder. When I used LSD at 13, I began displaying signs of nervousness and paranoia with a constant discomfort with social interactions. This was a complete shift in my behavior before using the drugs. Just a week after using the Blaze, I went from dressing like a bright teenager to a complete slob because it was considered cool among other drug users. Around the age of 14 to 16 I had a complete break from reality. The dormant gene of schizophrenia I inherited from my mother's side of the family manifested and completely ravished my life until I stopped all drug use at age 18 to enter the military.
I went through several years of rehabilitation on my own while in the military. Finally the psychosis morphed into acute anxiety and schizoid disorder, a mild form of schizophrenia, both which were probably affected by a less noticeable form of depression. After I left the military, I went from living the military lifestyle overseas in Europe to living in my hometown attending college. The reverse culture shock created a pervasive anxiety that destroyed my attempts at healthy social life and caused me to obsess over my college grades to a point where I experienced two debilitating nervous breakdowns. Each nervous breakdown resulted in debilitating exhaustion that affected my ability to complete even the simplest of tasks, with the first nervous breakdown lasting about 1-1.5 months and the second last around 3 months. As a result I was forced to either retake the classes I was enrolled for or settle with the grade when the semester ended.
Finally I received psychological help and was put on clonazepam for short-term anxiety. After several years, my anxiety became manageable, but my school performance and motivation began to decline. I graduated with a high GPA of 3.6/4.0, but at much social and professional loss. My social life was superficial at best. At graduation, I discovered that I had adult ADHD that carried over from childhood. The ADHD needed to be treated with medication. I am now being treated for anxiety and depression as well as ADHD with medication. I had to pay almost 17 years of my life and most likely I will need to take anxiety and depression medication for the rest of my life because I aggravated the genes I inherited from my family tree with the use of LSD and the Blaze. If I hadn't used those drugs, I would have likely not have suffered the kind of brain damage LSD caused me.
The important point for anyone reading this is that I have experienced a lot of psychological disturbance because I used LSD. If you are the 2-3% of the population with rare family lineage that doesn't genetically predispose you to even the possibility of mental problems, then I would say you could use any drug you want and not undergo deterioration in your behavior. However, if you have dormant genes that come from close relative or even distant relatives, such as my mother's aunt with schizophrenia, you will likely aggravate those genes with the use of LSD because of its destructive effects and the stress it causes.
If I hadn't used drugs I would have mostly suffered with just ADHD, but the medication I used as a teenager would have most likely improved my behavior. My life would have been fairly normal or possibly exceptional because of my physical and mental qualities. I know that the price I paid for using drugs was at least about 17 years of my life.
Some people may have the propensity for anxiety or depression only, but even if the gene for the mental problem is dormant or from a distant relative, you will likely experience a shift in behavior characteristic of the gene that you carry. If you have depression, the use of LSD will shift your mindset and behavior toward a more depressed personality that may take therapy or many month if not years of sustained self-improvement to correct. The same with anxiety, if you take LSD, anxiety will either be aggravated as a dormant gene or amplify the active gene, so that from that point forward you feel more anxious in your everyday life. Another warning is introversion. If you are susceptible to introversion, drugs can lead to extreme cases of shyness and/or preference to less stimulating environments. You could be a complete extrovert as I was until I used LSD, then my parent's genetics that I inherited, lead to the propensity toward introversion, which ultimately manifested into utter isolation. Even if I was with peers, I was isolated in my head and felt uncomfortable just being in the presence of others.
When I experienced my first bad trip, from that point forward all my LSD trips were bad trips. I also experienced intense discomfort when using the Blaze. I eventually continued to use drugs but often removed myself from the social situation I used to get the drugs. Then, I isolated myself so that I could experience some enjoyment from the drug. My personality was prone to repeated drug use even though I was experiencing aversion to the drugs. One positive is that today I don't go near anything that alters my mind because when I did use drugs, I developed a very strong aversion to mind altering substances including caffeine.
The one positive of LSD is the philosophy of life I have developed because I spent many years of life experiencing intense inner struggle and pain. I was able, overtime, to morph my philosophy on spirituality and my perception on living life into a very lucid understanding with regards to the big picture of a human life. Many of the intangible ideas of quantum mechanics and advanced spiritual thought as well as how to live my own life, that are often misunderstood and neglected by the masses, were already developed in my mind or held tentatively in my mind before I learned about the idea from a more prominent thinker or scientist. I even pondered the ideas of Jesus and the Buddha before I learned them from their source. This belief system has allowed me to answer the most important questions in life and has allowed all my life experiences to become influenced by their answers.
I wouldn’t want to go back in time and relive my life because I am certain of my place in relation to my higher power. I am excited about where my life will end up and the evolution of my eternal soul. The excitement isn't always visible in my behavior, but it always keeps me company when life gets the most difficult providing a foundation of inner resilience.
If you believe you are the top 2-3% of people that don't have a genetic factor that could affect your mental state and behavior in an unhealthy way, then I would say use drugs once or twice to expand your inner awareness and self-knowledge. Hallucinating with drugs can lead to immediate and a life altering spiritual experience?
Dr. David Hawkins says that hallucinogenic drugs are way to experience spiritual states that the likes of Jesus and the Buddha spent their lives to achieve. For that reason, I would endorse the use of hallucinogenic drugs for a small portion of the global population; the rest of the population should avoid shortcuts to spiritual enlightenment. One of the benefits of hallucinogenic drugs though is the often lifelong pursuit of spiritual evolution to achieve the state that was experienced while on the drug. From experience I can testify that once you see the world on hallucinogens, you will understand how everything fits together. Dr. Hawkins says, you will feel uninhibited spiritually because all the blocks to the most spiritual experiences will fall away. He also states and I can say from experience, many people will spend the rest of their lives chasing an experience that usually takes many, many lifetimes to achieve. This means the drug will likely not only affect your genetic propensity for mental problems but will most likely steer your life down a path toward spiritual growth, which I think is a positive reason to use the drug, but hardly worth the pain if you create even a year of behavioral issues and mental disturbance as a result.
Dang straight. I spent 40
Dang straight. I spent 40 years unable to connect with people until shrooms dissolved the invisible wall. Believe me, I tried. And then, there it was. My cell door was wide open and I could come and go as I pleased. The effect seems to be permanent.
Unsure
I'm 15, almost 16 and a friend of mine has suggested we do acid next week. He has done it before but i haven't. I have done weed and booze and mdma but that is pretty much it. I want to do it but i'm a bit scared. Can it damage your mind? And i don't know my friend that well, will the lack of trust lead to a bad trip? Thank you :)
Don't use it if you are not certain
Don't use hallucinogenic drugs if you are not prepared in mind, body, and soul for the experience. You need to do a thorough pre-evaluation checklist with a group of close and trust-worth friends before even considering the use of LSD or other similar drug. Their is only one reason and benefit to using the drug, and a laundry list of reasons not to use the drug. Also, only a small segment of the population is capable of creating a productive experience while using LSD, even if they think they say they are have a good time. Most likely they have nothing more than a juvenile reason to use the drug, which is the most important reason not to use the drug. The only reason to risk the potential destruction it can cause is if you are doing it to expand your consciousness and can have someone you look up to and trust to tell you the truth if LSD is the wrong thing to use for expanding your consciousness when that is the case.
Also, read my post further down possibly on the next page regarding my list of important points you want to consider be taking a trip.
LSD
When I was 19 I tripped every weekend; I LOVED it...it was an amazing experience - they way everything looked through your own eyes was nothing less then pure beauty. However; now 14yrs later I wonder if all that tripping really effected my mind. I really cannot remember things that I should....I just wonder if the LSD has something to do with it. To the 15 year old you really need to slow down. I understand wanting to experience things but you have the rest of your life ahead of you; one bad trip could screw that up. Also believe me you don't want to feel how I do now; ignorant for not knowing many things I should.
Unsure
Are you nuts? No of course you aren`t.
You don`t need drugs to live and to be happy, for God`s sakes!!!!
Change your ideas and use your mind, your brain for good things in life, and mainly to like, love and appreciate yourself and your innate born qualities. I`m sure that you have much more qualities than errors.
You are able to change what you think. Anyone can.
God Bless you and for God`s sakes Take extra good care of yourself!
A simple happy life is much, much more interesting to you too.
dont do any hallucinagensss
dont do any hallucinagensss pleaseee anyone.
the long term affects are so scary.
it fucks with your mind and im just looking out for you.
Its not cool.
Geez kid, if you read the
Geez kid, if you read the other comment that said "LSD is an *incredibly* powerful drug, and bad trips do happen, generally to people who are mentally unstable, depressed, or otherwise have serious issues.". It sounds like you might have issues if you've already tried "weed and booze and mdma" at your age.
If you're scared and don't trust your friend that well then you shouldn't do it, it sounds like a recipe for a bad trip. Maybe you should graduate high school and get a college degree beforehand. To be honest, you're not going to get much out of it at your age when your brain is still developing, if you waited until you're more educated taking LSD would be way more beneficial. If by "damage your mind" you mean rewire your brain, that's what it can do but it's not neurotoxic as far as I know.
REPLY
Don't you DARE do acid! You are way too young to be doing it, I should know... I am 20 years old and I did acid and I JACKED UP my mind. I lost memories, and a lot of other things that I'd rather not say. Please trust me when I say that I wish I had never done acid in my life and please please PLEASE listen to me when I say that you should deffinately not do it. And your friend should stop while he has a chance too. Please listen and I wish you the best.
cmon dude
dude seriously, you needa get your head checked out cause lsd is one of the safest chemicals known to mankind.dont draw people away from it just cause you obviously are mentally handicapped and your mind cant handle it
trying to remembering a hallucenogenic
Can anyone help me remember a powder back in the 60's (I am now in my mid 70's). it was really a hallucinogenic. we snorted it. it was very powerful. Seems it was an animal tranquilizer but not sure. It didn't take long after snorting it to make the room and things move in slow motion. It was not LSD! It was not mushrooms, it was something my son gave to me when he was a teenager back in the 60's. It was well known as something very strong, not piotee or any indian root. It was powdered and didn't take much to really get loaded. You certainly couldn't drive with it or do anything except just set down somewhere and trip on out. Please email me if you are old enough to remember what this was. I am finishing up writing a book and need the name to include in a story withing the book. Thanks.
Hi Charlie Clark Can anyone
Hi Charlie Clark
Can anyone help me remember a powder back in the 60's. Seems it was an animal tranquilizer............
They called it "Angel Dust"
Its horse tranquilizer.
sounds like it could have
sounds like it could have been ketamine yeah, or possibly DMT
ketamine
It was ketamine. My good friend is currently in the throws of a particularly rampant psilocybin trip. Happy trails!
drug in my food in county jail
my food was injected with some type of narcotic to have mental effects on me.my symptoms were lockjow,paranoia, numbness of gums,speech impediment,changing color and strong smell in urine,ringing of the ears,nervous,bloody nose up to 4 times a day,salivating more thin normal. some of these symptoms faded a way and some still exist. it hapend to me in jail . any one know what drug use to affect me this way ? please help me if u know ( thank you )
My first acid trip/ tips/ idk (:
( im not trying to educate anyone on Acid, i am no expert, just a lover of it.) This little passage i wrote isnt about informing you on the goods and bads of acid, its just what i remember of my trip so you can decide if its for you or not.) Hi, my names Brad. I'm 16 and have been smoking maryjane for quite some time. I have just recently decided to try a new type of drug other than marijuana ( i dont even call it a drug to be honest its a fucking plant it grows.... ) and some pills like xanax, addy percs, you know the easy to get teenager shit. Well out of nowhere my friend said this while we were sittin in my car. ( we all hang in my car and smoke and chill all day, ujelly? ) I wanna get some of that acid. My reaction ( no joke ) ARE YOU STUPID OMG THAT STUFF DESTROYS PEOPLE AND RUINS LIVES. Well I just took my first hit of acid about a month ago, AMAZED. This is the greatest thing in the world. My trip was amazing! Except i was dumb about it...Me and my friends went over to this kids house who is on all the harder drugs like crack , and he was about to drop us each a hit of acid. His basement was blood red, with some of the scariest things i have ever seen hanging on walls/drawn on walls. He even has a fucking pet weasle that just runs around in his basement. Well we each get our drop, sit there for an hour, and we all say this. This shit is wack dude. we werent feeling any different at all. He told us to look in the mirror. (My pupils were seriously covering my whole eye dude, like there was no color to my eyes except white and black. Thats the only negative thing , your dialated pupils). But yea we thought it was some bullshit so he offered another hit, i said i dont care lol, so i took another. shitty thing is tho we decided to leave ( WHY DID WE DRIVE?? IDK EITHER the guy even offered us to stay the night ) after we got our second hit...so i drop off my friends and thats that. im almost home...like seriously a road that is completely straight and only a mile long until im home. and then my friend who i have been talking to and looking at this whole time FLEW into the backseat!!!! he was wearing a white coat and i saw him turn into a streak of white and just zip into the back. i was like damn wtf, then i realized i was completely alone, and i just dropped him off like 10 minutes ago! aha!!!!!!!!!! now i started getting pumped becauase i thought i was starting to trip...and i was. the road zigzagged. straight up. just zigzags and some purplish green tint to it. i somehow made it home. look at my house, it looked like jello, just wouldn't stay still lol. i get inside, and sit down on my couch, and everything started to breathe, i could hear it breathe, watch it breathe and feel it breathe! my walls were just nonstop breathing! like they would all move far away, then come in close, then far away! aha it was amazing i probably watched my walls for an hour, then i needed a cig, so i go to my backyard. ( i was standing on my concrete platform with grass on two sides and my house on the other two.) and i started smokin my cig, lookin at everything, then the greatest thing of my life happened. The grass in my lawn, slowly , went from ripples, into WAVES. they were crashing into my knees! i could feel the grass! but i didnt move at all, i just stood there with a tide of grass rolling at my knees! And then i went inside. and then some bad stuff happened, a few dozen people somehow got into my house ( not really, i was trippin ) and were following me into my room , not kidding it was weird as hell. We all pile into my room and i sit down and start looking at them, they looked at me then just flew straight up and dissapeared into my roof. now im the kind of kid who would have shit his pants and grabbed the 9mm from my safe and started busting people because of being so scared, but i just told myself, they arent real, its the acid, they are just here to make you have more fun... well they all left except for one, the one in my closet, he sat there all night watching me do all my regular high activities... i even stared back at him for awhile. Now at the time i didnt think anything of it...but as i read about other peoples trips and ideas about acid and tought more about it...i really wasnt in the same universe, it couldnt have been. cause everything was so vivid and real, but if anyone has ever seen that movie Insidious , that can describe what tripping is like, you leave your body and go to a different world where everything is new and everything is amazing. Except its not scary, its just enjoyment. Like my friend who called me the next morning to describe his trip said he loved it, he told me he literally sat from 1am-3:30am, in his bathroom, looking at a towel, because he thought it was amazing!
People you saw
A book which may help you understand the people you saw. This Present Darkness by Frank Perette, it is suspenseful and a thriller. We were camping and I read this book sitting next to a camp fire in the middle of the night, after everyone was asleep.I could not put this book down after first chapter or two and read by a camp fire.The book helped me understand a lot and give me insight. Frank Perette has written many more but nothing effected more or taught me like his first book: This Presence Darkness
Yo man, Im right there with
Yo man, Im right there with ya. I love acid soo much, the first time I tripped was on I shit you not 7 hits of acid, I've loved it ever since. It has opened my eyes to many things, but you have to have a strong mindset and know what's going on all of the time. My friend didn't do that so well, nearing the end of our major tripping he started to freak out and I had to coax him through it. I have done acid many times after that, and I will always Tripp on CID. Good trips to ya man, peace.
Haha I didn't feel like typing my Tripp, to lazy, maybe I'll post it someday.
really
dude your 16 why do want to throw your life away with freaking drugs....i mean you could be anything you want to be in life......but its not none of my buisness so good day and best of luck to you
LSD
With acid it is a case of what it can do, not a case of what in necessarily does, People will talk in a dogmatic way from either the stance that it is harmless, or deadly. Either positions can be true, and you can't dogmatically state what is is like. That is naive. To talk about physical harm is naive too, as the main danger from the drug is mental. I took hundreds of acid trips way back in my youth, which was in the 1970's. The amounts in a dose were in reality (and officially) far greater in the 1960's and 1970's. On commencement I would take 1 at a time, and did this quite a number of times. It felt to me as acid was a beautiful drug which was very productive, and which gave great insight and opened up a whole new world. It was good for me. Some just know that aspect. I thought that the scare stories were all bullshit. The doses I would take started at 1 and gradually increased up to 4 or 5 at a time. Then one day it showed me what it was capable of, and what a lesson that was. I took 2 tablets of an American LSD which were incredibly strong, carrying a dose that was many times over the normal. This took me apart. I tried to kill myself by throwing myself off a bridge, because the trip was so overwhelming and frightening. Then I went crazy and had to be hospitalised. It took many people to stop me in my state, and I had to be strapped down. I had to be filled with goodness knows what to calm me down, and had to be watched continually. My state of mind lasted for many months, with amazing flashbacks that would send me into trips all day long. I have had breakdown after breakdown associated with this trip, and never been the same since. Continued HPPD continues from that to this day, and no doubt it will to the end of my life. It does annoy me when people who do not know what they are talking about talk with great authority on the matter, saying it is not bad at all and as bad as this or that drug. The drug can be the worst there is, not only deadly to the body (indirectly) but to your soul and mind. With LSD though, as said, it is a case of what it is capable of doing not what it will necessarily do. It can be so gentle and beautiful, and is very often that way. That is all some know about it, taking tiny doses in controlled circumstances. You have to be aware of what it can do, though it is only likely to do these things in much higher doses than are normally taken these days. Obviously you should not go near it if unbalanced in any way. You do not have to be unbalanced to have a bad experience though, as in large enough doses it can overwhelm anybody. It is impossible to say that somebody was unbalanced beforehand, and that is why they had a bad experience. To do that they would have to have been analysed professionally beforehand. For my own part, I was totally balanced before this devastating trip, otherwise I would not have been able to take increasingly large doses. It is a fact that in large enough doses (and the wrong circumstances) it is capable of taking anybody apart.
Shrooms/Acid Demonize You!
i have done lots of different drugs for a long time now. booze, pot, hash, extacy, mdma, cocaine, salvia, acid, and now recently i have done shrooms. i did lots of mushrooms over the weekend, and after being alone with my thoughts i learned how much smarter you become while on them, in the sense that you think of things in ways you have never thought before. after doing them i have learned that they leave your mind open to outside forces and information, and demonic possession. i now truly understand that the mushroom/lsd high opens the gateway to the spirit world, and leaves your body and mind wide open and vulnerable to possession. it was while on this trip that i have decided to quit all the drugs that i have been hooked on for years now. my way of thinking, especially on the subject of drugs, will never be the same again...
SAME
When i was on shrooms, i had been abusing drugs daily before that and started to get bad grades in college. I had very long hair and looked so much like a stoner, smoked cigaretts and my life was going down from being the basketball and football star that i used to be. I did a lot of stronger and hardcore drugs than shrooms but i took 3g's of it with 3 of my buds. It was a mindblowing experience. we took them on the beach and had a lot of fun and were all tripping out. But i got into deep thought as i do most of the time when i trip but this thought was different. It made me realize what was important in life and what path i was starting to go down instead of where i used to be and I thought of my parents some of the time in how proud they used to be in me when i used to dominate sports to now, partying everynight coming home around 3 a.m. every night i come back home from college and everything. Since then i returned to my college that i was planning to drop out of, continued playing sports, quit cigaretts and other drugs, I occasionally smoke weed because it's not that bad for you, I have a clean haircut (mom was very proud) and am trying to focus on my career in Economics. Mushrooms saved my life lol
WOW I am so glad to hear this
WOW I am so glad to hear this (not that I want you to suffer in any way) because I feel the same exact way. I have never done shrooms or LSD, but back in April/May I was going through a really hard time and did MDMA probably 20-30 times just in that short two-month span. It scares me because I dont feel like the same person anymore. I tried to tell my family but I dont think they took me very seriously and figured that since I managed to work and get good grades that I was fine. Well Im not. Ive been drinking since I was 12, smoking weed and hash since I was 14, and have done cocaine a handful of times as well as mdma dozens of times. I agree that it opens your mine to a certain vulnerability...damn Im so happy that Im not alone! People think Im crazy whenever I say that drugs open your mind to the spiritual world. It is SO true though. And I am Christian. Anyways, I haven't done mdma since May and don't plan to ever again, even though I think about it almost every day. I dont want to do drugs anymore either. They seriously f*ck with your head. I feel like they seriously have permanently altered my mind. Do you think the mdma could do that, that severely? Ive been trying to do some research online but haven't really found anything useful. Thank you for posting this.
You did not take MDMA 20-30
You did not take MDMA 20-30 times in a short two month span. That is once every two or three days and you would not be able to feel it after week two or three (you'd last a month if you're a champ) why would you lie on a site like this? At that point your brain would be incapable of creating the necessary chemicals for rolling (serotonin , norepinephrine , and smaller amounts of dopamine) gtfo with your stories, you don't know the definition of being a candy kid.
are shrooms bad for u?
i have heard things about doing shrooms:
i heard they stay in ur spine forever
i heard that they make ur eyes farther apart
cause long term negative cancerous effects on ur body and brain
are any of these true, false???
please explain and use actual sources (doctors, books, clinical studies etc...)
not just random stuff you heard, because obviously i've heard it.
and if i haven't and there's no backing, i'm not interested, since i'm already confused enough.
also, i don't need comparisons between LSD and shrooms bc i have never done LSD and don't plan on ever doing it either.
only weed and shrooms and the drank thanks for the help researchers!!
When you take shrooms does it
When you take shrooms does it go up your spine? i had an experience where i believe i had my drink spiked and i felt something in my spine and go up in to my brain and i was in the lower astral realms can shrooms do this to you
start off by looking for
start off by looking for examples and facts on any site but a comment forum haha..seriously though dont believe any of that bull it may stay in your spine but who cares you cant re-trip if you crack your back and who in the world is gonna pay 10000 dollars for a spinal tap?..i have no sources but your best bet is to type in mushroom facts on google and find stuff on the..for the record though lsd and psyliocybin (drug in shrooms) are just about the least harmful chemicals and or drugs known to man..lsd is probably even safer cause it doesnt screw with your stomach
Are you kidding me? LSD is
Are you kidding me? LSD is one of the MOST toxic chemicals known to man.
No
It is actually less toxic than Vitamin C my friend.
Actually, it's less toxic
Actually, it's less toxic then cafine. It's one of the least toxic drugs, it does not do any harm... It's called research, dude
You might be right
If you use caffeine excessively everyday for 30 or 40 years, then you might achieve the brain damage resulting from one use of highly potent LSD dose. As far as I know, LSD puts enormous stress on the body resulting in a cascade of stress hormones that soak your brain and other organs for several days in stress hormones. What I know to this point is the stress alone will lead to the destruction of the brains ability to communicate information interdependently among regions. Also, the common sense assumption is that to achieve an experience of that magnitude, which can ultimately redefine your relationship to life indefinitely, good or bad, will come at a cost to you physically, mentally, and spiritually. The most likely aspect to be affected equally among any user of LSD is the brain damage is causes as it changes the brains chemical balance for as much as 12 to 16 hours and remains in the system for days afterward. Next time you are tripping on LSD, check if you discover that you are beading with sweat at the forehead. I wouldn't doubt that you would experience intimately the physical destruction of you physiology much more acutely if you removed the positive sensations. From what I know, you only experienced the negative sensations, which you most likely fail to acknowledge because your senses are all amplified so when negative sensation arises during a trip, your other senses overwhelm the single negative sensation you might be experiencing. Also you most likely are in intense pain during the experience, but the pain isn't noticeable because of the amount of endorphin-s and h-adrenaline your body is creating. Without the cascade of positive brain reactions, my assumption is that most people would be thriving in pain and mental anguish.
Thats some really deep shit
Thats some really deep shit and i agree with what you are saying fully..
lsd
lsd saved my life. as a person who was a drug addict for years (20 plus) i don't advocate the use of drugs at all. but i will say what psychiatry tried to do for me didn't work. heroin didn't work. weed didn't work. co-dependent relations didn't work and it was all because I was getting in the way. i couldn't leave things alone and just be happy. i can now. i sleep at night better. and i get shit done. that's all that matters to me. and i don't have to trip anymore. it's almost like it made itself redundant...
lsd
LSD is a touchy subject...it is very true that everyone acts different. My thoughts of the drug is that you should be a rather happy person who enjoys life (if your depressed or have ever thoguht of suicide please dont acid) when taking the drug please be with friends who are also on the trip and maybe a "babysitter" someonoe who is sober and that you know well. You MUST remind yourself that you are on lsd...aka crazy shit is going to happen, but everything will be okay because tomorrow will come. My feelings for acid is that its AMAZING..changed my life for the greatest in ways i never thought possible
LSD
LSD can be fun in the moment (or not). But I know a guy who used alot back in the day. One day he took 20 hits!! He no longer uses, but now he is a recluse, social phobic. He freezes up in conversations i.e cant think ... and will have panic attacks. His life has changed dramatically to the point of being incapacitated. I am trying to find research about specific effects on cognitive functioning due to long term or extreme use of LSD. Although I've found general info (LSD affects reality testing, communication), I am hungry for more. ...And WHAT to do about it. I am wondering if anyone else out there has problems like this and if anything has helped.
CoMMon SeNse
...... I MEAN YOUR AWFULLY LAZY AND YOUR PURPOSE IN LIFE IS ALL HAZY, IF YOU JUST KEPT THAT RECEIPT YOU CAN TAKE THAT BRAIN YOU BOUGHT,BACK, AND GET THAT TRAIN OF THOUGHT BACK ON TRACK BY EATING SOME OVERLY PRESCRIBED PROZAC...
but really be real with your friend (be strait-forward) and tell him that its all in his head..the moment he realizes that he'll come back ..SLOWLY BUT SURLEY..LIFES A JOURNEY IT AINT OVER YET, O and it ok to be "mean"
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