activities for teaching biology

In the lab, DNA, students extract DNA from their cheek cells and relate the steps in the procedure to the characteristics of cells and DNA. Students learn about DNA structure and replication during the intervals required for the extraction procedure.

Download Student Handout: PDF format or Word format

Download Teacher Preparation Notes: PDF format or Word format

In the lab, Using Blood Tests to Identify Babies and Criminals, students learn the genetics and immunobiology of the ABO blood type system, using simple chemicals and logical reasoning to solve a murder mystery and to determine whether two babies were switched in the hospital.

Download Student Handout: PDF format or Word format

Download Teacher Preparation Notes: PDF format or Word format

In the simulation activity, Dragon Genetics – Understanding Inheritance, students mimic the processes of meiosis and fertilization to investigate the inheritance of multiple genes and then use their understanding of concepts such as dominant/recessive alleles, incomplete dominance, sex-linked inheritance, and epistasis to interpret the results of the simulation. This activity can be used as a culminating activity after you have introduced classical genetics, and it can serve as formative assessment to identify any areas of confusion that require additional clarification.

Download Student Handout: PDF format or Word format

Download Teacher Preparation Notes: PDF format or Word format

In the lab, Dragon Genetics: Independent Assortment and Gene Linkage, students learn the principles of independent assortment and gene linkage in activities which analyze inheritance of multiple genes on the same or different chromosomes in hypothetical dragons. Students learn how these principles derive from the behavior of chromosomes during meiosis and fertilization.

Download Student Handout: PDF format or Word format

Download Teacher Preparation Notes: PDF format or Word format

The activities in Genetics help students to understand the basic principles of genetics, including concepts of recessive and dominant alleles, relationships of phenotype to genotype, Punnett squares, and pedigree analysis. The introductory section on inheritance of albinism demonstrates how understanding meiosis and fertilization provides the basis for understanding inheritance and Punnett squares. The next two sections, Coin Toss Genetics and analysis of class data on the sex makeup of sibships, help students understand the probabilistic nature of Punnett square predictions. The final activities analyze the genetics of sickle cell anemia and pedigrees for families with albinism and achondroplasia.

Download Student Handout: PDF format or Word format

In the lab, Diffusion across a Selectively Permeable Membrane,  students investigate the effects of molecule size on diffusion across a synthetic selectively permeable membrane (dialysis tubing) and discuss applications to understanding the selectively permeable cell membrane.This activity includes a demonstration of osmosis (diffusion of water across a selectively permeable membrane).

In the lab, Moldy Jell-O, students design experiments to determine how substrate and environmental conditions influence growth of common molds. Students carry out their experiments, analyze and interpret their evidence, and prepare a report.

Download Student Handout: PDF format or Word format

Download Teacher Preparation Notes: PDF format or Word format

In the lab, Is Yeast Alive?, students evaluate whether the little brown grains of yeast obtained from the grocery store are alive by testing for metabolism and growth.

Download Student Handout: PDF format or Word format

Download Teacher Preparation Notes: PDF format or Word format 

We invite comments on this Hands-On Activity and the accompanying Teacher Preparation Notes, including suggestions for other teachers who are planning to use the activity, useful preparatory or follow-up activities, additional resources or any questions you have related to the activity, or a brief description of any problem you might have encountered. If you have a relevant Word document you would like to have posted on this comments page, such as a version of the protocol you have used in your classroom, or if you would prefer to send your comments or questions in a private message, please write Ingrid Waldron at iwaldron@sas.upenn.edu.

In the  hands-on activity, Mitosis, Meiosis and Fertilization, students use model chromosomes to simulate the processes of mitosis, meiosis and fertilization, and they answer questions designed to promote student understanding of these processes. The principle that genes are inherited through the processes of meiosis and fertilization is demonstrated by analyzing a simulation of meiosis and fertilization that uses model chromosomes with different alleles of a gene. Students also learn how a mistake in meiosis can result in Down Syndrome.

Download Student Handout: PDF format or Word format

Download Teacher Preparation Notes: PDF format